Sedatives & Hypnotics
Sleeping pills, barbiturates and muscle relaxants — depressants with razor-thin margins. From Ambien to Seconal: these slow the brain and breathing. Mixing with opioids or alcohol multiplies the danger.
3-5xoverdose risk when depressants are mixed (studies)
9profiles in this category
Zolpidem (Ambien/Stilnox)
White/pink oblong tablets (5–10 mg); 'Ambien' imprint
Effects & risks →
Secobarbital (Seconal)
Red-orange capsules (50–100 mg)
Effects & risks →
Carisoprodol (Soma)
White 250/350 mg tablets; 'Soma' imprint
Effects & risks →
Cyclobenzaprine (Flexeril)
Yellow/orange 10 mg tablets (Merck); white 5 mg
Effects & risks →
Pentobarbital (Nembutal)
Yellow capsules, pink injectable solution (veterinary), powder
Effects & risks →
Butalbital (Fioricet/Fiorinal)
White/blue tablets with caffeine + acetaminophen or aspirin (50/325/40 mg)
Effects & risks →
Pregabalin (Lyrica)
White/orange/red-and-white capsules (75–300 mg)
Effects & risks →
Zopiclone (Imovane)
Blue film-coated tablets (3.75/7.5 mg); blisters branded 'ZOP'
Effects & risks →
Eszopiclone (Lunesta)
White/blue film-coated round tablets (1–3 mg)
Effects & risks →