Opioids
Heroin, fentanyl, painkillers and the nitazenes — the deadliest category in the drug supply. Opioids suppress breathing. Most overdose deaths in the US, Canada and Europe now involve fentanyl or its analogues — often mixed into drugs the buyer never asked for.
Heroin
White/off-white powder (US) or brown base powder ('sugar brown'); black tar (Mexico)
Fentanyl
White powder, pressed pills, counterfeit oxycodone — often invisible when mixed into other drugs
Fentanyl HCl (powder)
Fine white crystalline powder, indistinguishable from other white powders
Acetylfentanyl
White/tan powder, sometimes sold as 'synthetic heroin' or pressed into pills
Furanylfentanyl (Fu-F)
White/yellowish powder or pressed tablets
Methoxyacetylfentanyl
White/off-white powder
Etonitazene
White/yellow/off-white powder, pills, or e-liquid for vaping
Isotodesnitazene
White/yellow powder, often mixed into heroin or counterfeit pills
Oxymorphone (Opana 40 mg)
Pink/octagonal ER tablets (Opana 40 mg); white IR tablets
Morphine 60 mg
Round ER tablets imprinted 60 (purple/orange by brand); oral solution; injectable ampoules
Hydromorphone (Dilaudid 8 mg)
Small triangular white tablets ('8mg triangles'); clear injectable liquid
Oxycodone (Roxicodone 30 mg)
Blue 30 mg IR tablets; also white pills with various imprints
OxyContin
Round ER tablets (OC imprint); reformulated 2010 to deter crushing
Codeine 30/500 mg (co-codamol)
White tablets (30 mg codeine / 500 mg paracetamol); purple/clear syrup
Hydrocodone 10/500 mg
White/oblong tablets imprinted Watson 540-style; capsules historically
Hydrocodone–Ibuprofen (Vicoprofen)
White oblong tablets (7.5 mg hydro / 200 mg ibuprofen)
Meperidine (Demerol)
White capsules (50/100 mg); clear injectable solution
Methadone
Orange/red diskettes (40 mg), liquid (cherry), tablets, injectable ampoules
Suboxone (buprenorphine/naloxone)
Orange sublingual films (2/0.5 mg, 8/2 mg) or hexagonal tablets
Subutex (buprenorphine)
White sublingual tablets (2 mg, 8 mg), hexagonal imprint
Fentanyl patches (Duragesic 12.5 mcg/hr)
Tan rectangular transdermal patches (12.5–100 mcg/hr), gel or matrix type
Xylazine (Tranq)
No street form of its own — found mixed into fentanyl/heroin (white/beige powder) or pills
Butorphanol (Stadol)
Clear nasal spray bottle or injectable vials (1–2 mg/mL); vet brands (Butomidor) common
Dihydrocodeine (DHC)
White tablets (30 mg) or liquid; OTC-low-dose in some EU countries
Opium
Dark brown/black sticky latex balls or bricks; tincture (laudanum) amber bottles
Sufentanil
Clear ampoules (5–50 mcg/mL), hospital-only packaging
Oxycodone–APAP (Percocet generic)
White/yellow tablets (5/325, 10/325 mg) with various imprints; 'PERCOCET' brand bottle
Tianeptine (Gas Station Heroin)
Capsules, tablets, or liquid shots sold at gas stations, vape shops, online as 'dietary supplement'
Kratom (Mitragyna speciosa)
Green powder, capsules, extracts, liquid shots sold at smoke shops/gas stations
Carfentanil
White powder — 100× fentanyl, dosed in MICROGRAMS; occasionally found in heroin/fentanyl supplies
U-47700 (Pink / U4)
White or pink powder, pills; sold online as 'research chemical'
'Gray Death' (Mixed Opioid Combo)
Chunky gray/gray-brown powder resembling concrete mix
Krokodil (Desomorphine)
Homemade injectable from codeine pills + gasoline + iodine + red phosphorus — dirty amber liquid
Purple Drank (Lean / Codeine Syrup)
Purple/pink cough syrup (codeine + promethazine) mixed with soda and candy; double-stacked cups
Tramadol (Ultram)
50–100 mg tablets/capsules; 50 mg/ml drops; IV ampoules
Tapentadol (Nucynta)
50–250 mg tablets; ER versions
Loperamide (Imodium) Abuse
2 mg anti-diarrhea tablets, blister packs; users take 50–300+ tablets
Brorphine
White/off-white powder, often purple-tinted when mixed ('purple heroin')
Metonitazene
Yellow/tan/off-white powder, pressed pills
Protonitazene
White/yellow powder or counterfeit pills
AH-7921
White/off-white powder or tablets; sold online as 'research chemical' around 2013–2015
MT-45 (IC-6)
White powder — 1970s compound revived as 'legal opioid'
W-18
White powder — 1980s compound sold as 'research chemical' mid-2010s
Naloxone (Narcan)
4 mg nasal sprays (Narcan), 8 mg (Kloxxado), 0.4–2 mg injectable ampoules, auto-injectors
Naltrexone (Vivitrol / Revia)
50 mg tablets; 380 mg monthly injection (Vivitrol)
Poppy Seeds & Poppy Seed Tea
Blue-black food-grade poppy seeds; tea brewed from unwashed seeds or dried pods (opium poppy, Papaver somniferum)
Akuamma (Picralima nitida Seeds)
Dried seeds ground to bitter powder; capsules or raw seed chewed
Isotonitazene ('Iso')
Yellow/off-white powder; pressed into counterfeit pills
2-Methyl-AP-237
White/off-white powder; China-export RC opioid
Diphenoxylate (Lomotil)
2.5 mg tablets combined with atropine (0.025 mg) — the atropine is the abuse-deterrent
Medetomidine
No street form of its own — detected as a whitish powder mixed into fentanyl/heroin, often alongside xylazine and BTMPS
7-Hydroxymitragynine (7-OH)
Tablets, pellets, gummies and concentrated 'shots' sold at gas stations, vape shops and online — far stronger than kratom leaf per dose
Etonitazepyne (NPE)
Off-white to yellowish powder, active in the microgram range; pressed into fake oxycodone/hydrocodone pills and mixed into heroin/fentanyl supplies
Para-fluorofentanyl (4-FBF)
White to off-white powder; found loose, in fake oxycodone pills, and mixed into heroin and cocaine supplies
O-Desmethyltramadol (O-DSMT)
White crystalline powder, sold online as a 'research chemical'; pressed into pills or dissolved for liquid dosing
Nalmefene (Opvee)
5 mg/0.5 mL single-dose nasal spray (bright blue device); hospital injection
Dipyanone
White-to-off-white powder and pressed tablets sold online as a 'research chemical'
Mitragynine (Kratom's Main Alkaloid)
Pure compound: white powder (research chemical). In practice it arrives inside leaf powder, capsules, shots and extracts
Kratom Shots & Extracts (OPMS-style)
Small 'energy-shot' bottles, gummies, concentrated resins and capsules — sold at gas stations, smoke shops and kava bars
Butyrylfentanyl
White/off-white powder; also pressed into counterfeit oxycodone pills
Cyclopropylfentanyl
White powder, indistinguishable from heroin or fentanyl
Valerylfentanyl
White/off-white powder
Acrylfentanyl
White powder; pressed pills
Ocfentanil
White powder; counterfeit pills
Etonitazepipne (N-Pyrrolidino Etonitazene)
White/yellow powder; increasingly found in fake oxycodone and heroin
Butonitazene
White/yellowish powder
Etodesnitazene (Etazene)
White/tan powder
Metodesnitazene
White/off-white powder
Cychlorphine
White crystalline powder sold by online opioid vendors
U-48800
White powder sold as 'research chemical' opioid
AP-238
White powder, sometimes in solution
Pentazocine (Talwin)
Tablets; historically injected after crushing ('T's and blues' with tripelennamine)
Nalbuphine (Nubain)
Injectable solution; diverted ampoules
Levorphanol (Levo-Dromoran)
Tablets (2 mg); injectable
Dextropropoxyphene (Darvon / Darvocet)
Pink capsules/tablets; combination pills with paracetamol
Tilidine (Valoron)
Drops, capsules and extended-release tablets (often combined with naloxone)
Ketobemidone (Ketogan)
Tablets and injection; diverted in Scandinavia
Sublocade (Buprenorphine Depot Injection)
Monthly subcutaneous depot injection given in clinics
Mitragynine Pseudoindoxyl
Semi-synthetic kratom alkaloid in high-potency extracts, shots and gummies
Dextromoramide (Palfium)
Tablets (historically 5–10 mg); illicit stock circulates in parts of Europe and Asia
Dipipanone (Diconal)
Tablets combined with cyclizine (Diconal); illicit leftovers and lookalikes
Codeine–Ibuprofen (Nurofen Plus) Abuse
Over-the-counter combination tablets (codeine 12.8 mg + ibuprofen 200 mg)
N-Pyrrolidino Isotonitazene (NPI)
Off-white to beige powder; pressed into counterfeit oxycodone and 'M30' pills
N-Propionitrile Chlorphine
White/off-white powder; identified in powders and pressed tablets
Spirochlorphine (R-6890)
White crystalline powder; found in 'heroin' samples and counterfeit pills
Protodesnitazene
Off-white powder; identified as both a precursor and a street opioid
Desnitroclonitazene
White to off-white powder; seen in powders and tablets in Belgium/EU
Fluetonitazene
Off-white powder; detected in counterfeit pill and powder samples
Isobutonitazene
White crystalline powder; found in 'oxycodone' counterfeit pills
N-Desethyl Protonitazene
Off-white powder; identified in post-mortem and seizure samples
o-Methylfentanyl (ortho-Methylfentanyl)
White powder; pressed into counterfeit pills; sold as 'heroin' or 'fentanyl'