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52 substances

Psychedelics

DMT, mescaline and the 2C family — mind-altering, not life-threatening at pure doses. Classic psychedelics have no known lethal overdose range — the real risks are psychological and behavioral: panic, bad judgment, accidents.

0confirmed lethal overdoses of pure classic psychedelics (published literature)
52profiles in this category
Schedule I

DMT (dimethyltryptamine)

White/yellow crystalline powder; also in ayahuasca plant brews

Effects & risks →
Schedule I

Peyote (mescaline cactus)

Small spineless grey-green cactus 'buttons'; dried slices

Effects & risks →
Schedule I

Mescaline powder

White/off-white crystalline powder (extracted) or brownish raw powder

Effects & risks →
Schedule I

2C-B

White/off-white powder or small pressed pills (often pink/purple)

Effects & risks →
Analogue prosecutions

4-AcO-DMT (psilacetin)

White/beige powder or fumarate crystals; pressed pellets

Effects & risks →
Schedule I

Psilocybin Mushrooms (Shrooms)

Dried whole mushrooms (golden-brown caps, blue-stem bruising), or ground into chocolate/tea; 'magic truffles' (sclerotia) in NL

Effects & risks →
Legal federally

Salvia Divinorum

Dried leaf, extracts (5×–60×), liquid tinctures; smoked or chewed

Effects & risks →
Unregulated

Amanita Muscaria (Fly Agaric Mushrooms)

Red-capped mushroom with white spots — the Mario mushroom; sold dried, in gummies, or extracts

Effects & risks →
Unregulated

Blue Lotus (Nymphaea caerulea)

Dried blue flowers smoked, brewed, or vaped; extracts

Effects & risks →
Schedule I

2C-B-FLY

Pellets or powder; benzodifuran analogue of 2C-B

Effects & risks →
Schedule I

DOM (STP)

White/off-white tablets or powder; often sold as 'acid' or 'mescaline'

Effects & risks →
Schedule I

Bromo-DragonFLY

White powder or liquid drops; benzodifuran psychedelic

Effects & risks →
Schedule I analog

LSZ (Lysergic acid 2,4-dimethylazetidide)

Blotter or liquid; LSD analogue

Effects & risks →
Schedule I analog; controlled EU

ETH-LAD

Blotter, pellets; LSD analogue

Effects & risks →
Schedule I analog; controlled EU

AL-LAD

Blotter, pellets

Effects & risks →
Analog prosecution

bk-2C-B (Beta-keto 2C-B)

White powder/pellets

Effects & risks →
Schedule I

LSD (Acid)

Blotter paper squares, liquid drops, microdots, gel tabs; often decorated

Effects & risks →
Prosecutable as LSD analogue

1P-LSD (and analogs: 1cP, 1V, ALD-52)

Blotter, pellets, liquid — indistinguishable from LSD in effect and form

Effects & risks →
Schedule I

5-MeO-DMT (Bufo / Toad Venom)

White powder (synthetic or extracted from Sonoran Desert toad glands); smoked/vaporized 5–20 mg

Effects & risks →
Schedule I components

Ayahuasca (The Brew)

Thick brown bitter tea brewed from Banisteriopsis caapi vine + DMT-containing leaves (chacruna/chaliponga)

Effects & risks →
Mescaline = Schedule I US; cactus legal to grow

San Pedro Cactus (Echinopsis pachanoi)

Tall columnar cactus sold at plant markets and botánicas; prepared as a slow-cooked tea/mash

Effects & risks →
Schedule I

Ibogaine (Iboga)

Root bark powder (Tabernanthe iboga), HCl extract, or Total Alkaloid; 3–5 g bark or ~15–20 mg/kg

Effects & risks →
Not a controlled drug — unregulated ceremony product

Kambo (Frog Secretion)

Burned dots on the skin; secretion of the giant leaf frog (Phyllomedusa bicolor) applied to open gates

Effects & risks →
DMT/bufotenin controlled US; seeds legal to possess most places; Syrian rue

Yopo / Cebil (Anadenanthera Snuffs)

Toasted and ground seeds of Anadenanthera peregrina/colubrina, snuffed; combined with Syrian rue (Peganum harmala) in modern use

Effects & risks →
Not federally scheduled US

Datura (Jimsonweed / Devil's Trumpet)

Spiky seed pods and trumpet flowers; seeds and teas — every part contains scopolamine/atropine/hyoscyamine

Effects & risks →
Food/legal — unregulated

Nutmeg (Myristicin)

Whole nutmeg seeds or ground spice from the kitchen; 5–20 g consumed

Effects & risks →
Seeds legal to possess most places

Morning Glory / Hawaiian Baby Woodrose (LSA)

Seed packets sold legally as ornamentals; 50–300 morning glory or 3–10 HBWR seeds chewed/extracted

Effects & risks →
Schedule I

2C-x Family (2C-E, 2C-I, 2C-C, 2C-D, 2C-P)

White powder, pellets, or pressed pills sold as '2C-B' or research chemicals

Effects & risks →
Schedule I

DOx Family (DOB, DOC, DOI)

Blotter or powder — the classic 'fake acid' alongside NBOMe

Effects & risks →
Schedule I

NBOMe (25I, 25C, 25B-NBOMe)

Blotter with designs mimicking LSD; sometimes powder; bitter metallic taste and tongue-numbing are the tell

Effects & risks →
Analogue prosecutions

4-HO-MET (Metocin) & 4-HO-MiPT

White/beige powder or pellets; fumarate salt

Effects & risks →
Schedule I

5-MeO-MiPT (Moxy) & 5-MeO-DIPT (Foxy)

White powder/crystals, dosed in the 5–15 mg range

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Not federally scheduled US

DPT (Dipropyltryptamine)

White crystalline powder; smoked, snorted, or IM'd (church tradition)

Effects & risks →
Schedule I

aMT (alpha-Methyltryptamine)

Off-white powder/crystals; historically 5–10 mg antidepressant tablets, now sold as powder

Effects & risks →
Legal alcohol product

Absinthe (Wormwood / Thujone)

Green anise-flavored spirit at 45–74% ABV; the 'louche' ritual with sugar and water

Effects & risks →
DMT = Schedule I US; harmalas controlled some regions

Changa (DMT Smoking Blend)

Herbal smoking blend — DMT-infused herbs (often mullein, damiana) plus MAOI herbs (caapi leaf, Syrian rue); looks like herbal incense

Effects & risks →
Unregulated plant; voacangine controlled some regions as ibogaine analog

Voacanga africana

Seeds and bark of an African tree; contains voacangine (ibogaine precursor)

Effects & risks →
Schedule I

5-MeO-DiPT (Foxy / Foxy Methoxy)

White powder or capsules; early-2000s club drug that still resurfaces

Effects & risks →
Unscheduled RC; psilocin analog risk

4-HO-MiPT (Miprocin)

White/off-white powder or capsules

Effects & risks →
5-MeO-DMT is Schedule I

Bufo / Toad Venom (5-MeO-DMT)

Dried secretion of the Sonoran Desert toad, smoked in a pipe; celebrity-retreat trend

Effects & risks →
Sold as 'legal' — contents often illegal or undeclared

'Mushroom' Gummies & Chocolate Bars (Gas-Station Edibles)

Branded chocolate bars and gummies sold in smoke shops and online

Effects & risks →
Schedule I

2C-E

White powder; milligram-dosed capsules

Effects & risks →
Schedule I

2C-I

White powder, pills, or blotter

Effects & risks →
Schedule I

DOC

White powder; DOSES OF 2–4 mg fit on blotter — repeatedly mis-sold as LSD

Effects & risks →
Schedule I

DOB

White powder; active at 1–3 mg — fits on blotter and has been sold as LSD, with fatal results

Effects & risks →
Not scheduled federally

25B-NBOH

Blotter or micro-pellets; sub-milligram doses sold as 'legal LSD/NBOMe'

Effects & risks →
Not scheduled federally

25I-NBOH

Blotter, pellets, powder; active in the 500–1000 µg range

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Not scheduled federally

4-AcO-MET

Off-white powder or pellets; 'psilacetin-family' RC

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Not scheduled federally

4-AcO-MiPT

Off-white powder/pellets; rare tryptamine RC

Effects & risks →
Not scheduled federally

5-MeO-MiPT ('Moxy')

White/off-white powder, pellets, or inside pressed 'ecstasy-style' pills

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Not scheduled federally

1cP-LSD

Blotter art paper; micro-pellets; liquid

Effects & risks →
Not scheduled federally

1D-LSD

Blotter, pellets, liquid — the current German/EU legal-loophole LSD prodrug

Effects & risks →