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Sedatives & Hypnotics

Butalbital (Fioricet/Fiorinal)

Street names: Fioricet, Fiorinal, Esgic

Butalbital (Fioricet/Fiorinal) — White/blue tablets with caffeine + acetaminophen or aspirin (50/325/40 mg)

What it does

  • Sedation, relaxation
  • Tension-headache relief
  • Mild euphoria

Key risks

  • Barbiturate dependence — tolerance builds in weeks
  • Rebound headaches drive overuse
  • Acetaminophen component destroys the liver at high doses

Overdose signs

  • Extreme drowsiness
  • Slow breathing
  • Confusion, slurred speech

📋Quick facts

Also known asFioricet, Fiorinal, Esgic
CategorySedatives & Hypnotics
Schedule / classSchedule III (US, combinations)
AppearanceWhite/blue tablets with caffeine + acetaminophen or aspirin (50/325/40 mg)
Street price~$2–$8 per tablet (diverted)
Legal statusRx-only, Schedule III; online grey-market sales widespread
Last updated2026-09-14
Sources: FDA, NIDA

Category comparison — Sedatives & Hypnotics

SubstanceClassTop risksStreet price
Butalbital (Fioricet/Fiorinal)Schedule IIIBarbiturate dependence — tolerance builds in weeks; Rebound headaches drive overuse~$2–$8 per tablet
Secobarbital (Seconal)Schedule IIBarbiturates: tiny margin between dose and death; Fatal in overdose, brutal withdrawal (seizures) — replaced by benzos in medicine~$15–$40 per capsule where diverted
Pentobarbital (Nembutal)Schedule IIVeterinary euthanasia drug — overdose is usually fatal; Narrow safety margin (barbiturate)~$30–$100+ per vial/capsule-equivalent
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does Butalbital (Fioricet/Fiorinal) look like?

White/blue tablets with caffeine + acetaminophen or aspirin (50/325/40 mg)

What are the signs of a Butalbital (Fioricet/Fiorinal) overdose?

Extreme drowsiness; Slow breathing; Confusion, slurred speech Call emergency services immediately.

How addictive is it?

Barbiturate dependence — tolerance builds in weeks Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.