Performance & Grey-Market Pharma
Naltrexone–Bupropion (Contrave)
Street names: Contrave, Mysimba
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Appetite suppression, mild stimulant effect (bupropion)
- Craving reduction (naltrexone)
⚠Key risks
- Bupropion lowers seizure threshold
- Misuse for stimulant-like effect is possible but weak
- Grey-market 'weight loss' bundles pair it with thyroid hormone — dangerous
✚Overdose signs
- Seizures
- Racing heart, agitation
- Severe nausea
📋Quick facts
Also known asContrave, Mysimba
CategoryPerformance & Grey-Market Pharma
Schedule / classRx-only — not controlled
AppearanceBlue tablets (8/90 mg), film-coated
Street price~$1–$4 per tablet grey-market
Legal statusRx-only; not a controlled substance
Last updated2026-09-14
Sources: FDA, EMA
Category comparison — Performance & Grey-Market Pharma
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Naltrexone–Bupropion (Contrave) | Rx-only — not controlled | Bupropion lowers seizure threshold; Misuse for stimulant-like effect is possible but weak | ~$1–$4 per tablet grey-market |
| Liraglutide (Saxenda) | Rx-only — not a controlled drug | Sold grey-market at huge markups with counterfeit/refilled pens; Nausea, pancreatitis risk | ~$200–$500 per pen grey-market |
| Phentermine (Adipex-P) | Schedule IV | Cardiovascular strain, hypertension; Dependence with prolonged use | ~$1–$5 per 37.5 mg tablet |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Naltrexone–Bupropion (Contrave) look like?
Blue tablets (8/90 mg), film-coated
What are the signs of a Naltrexone–Bupropion (Contrave) overdose?
Seizures; Racing heart, agitation; Severe nausea Call emergency services immediately.
How addictive is it?
Bupropion lowers seizure threshold Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.