Empathogens
Kanna (Sceletium tortuosum)
Street names: Kanna, Kougoed, Sceletium
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Mood lift, relaxation, mild euphoria (serotonin reuptake inhibition)
- Social ease
⚠Key risks
- SSRI-class activity — DANGEROUS with antidepressants (serotonin syndrome)
- No regulation of extracts
- Vaping concentrates unknown effects
- 'Natural SSRI' marketed without warnings
✚Overdose signs
- Serotonin syndrome (with combos): agitation, fever, tremor
- Nausea, headache
📋Quick facts
Also known asKanna, Kougoed, Sceletium
CategoryEmpathogens
Schedule / classUnregulated supplement
AppearancePowder, capsules, extracts, vapes
Street price$15–$40 powder; extracts $25–$60
Legal statusUnregulated supplement; 'natural antidepressant' marketing unregulated
Last updated2026-09-17
Sources: PubMed, NIDA
Category comparison — Empathogens
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Kanna (Sceletium tortuosum) | Unregulated supplement | SSRI-class activity — DANGEROUS with antidepressants (serotonin syndrome); No regulation of extracts | $15–$40 powder |
| MDMA | Schedule I | Overheating + dehydration (or fatal water intoxication); Serotonin depletion — multi-day comedown | ~$10–$40 per pill |
| 5-APB | Class B | Serotonin release + MAOI-like properties → serotonin syndrome risk; Long duration complicates dosing | ~$15–$40 per gram or ~$5–$15 per pellet |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Kanna (Sceletium tortuosum) look like?
Powder, capsules, extracts, vapes
What are the signs of a Kanna (Sceletium tortuosum) overdose?
Serotonin syndrome (with combos): agitation, fever, tremor; Nausea, headache Call emergency services immediately.
How addictive is it?
SSRI-class activity — DANGEROUS with antidepressants (serotonin syndrome) Dependence can develop with regular use.