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Sedatives & Hypnotics

Pentobarbital (Nembutal)

Street names: Nembutal, Yellow jackets, Pentobarbs

Pentobarbital (Nembutal) — Yellow capsules, pink injectable solution (veterinary), powder

What it does

  • Fast deep sedation → anesthesia

Key risks

  • Veterinary euthanasia drug — overdose is usually fatal
  • Narrow safety margin (barbiturate)

Overdose signs

  • Coma
  • Absent breathing
  • Pupils dilated then fixed

📋Quick facts

Also known asNembutal, Yellow jackets, Pentobarbs
CategorySedatives & Hypnotics
Schedule / classSchedule II (US)
AppearanceYellow capsules, pink injectable solution (veterinary), powder
Street price~$30–$100+ per vial/capsule-equivalent (rare, diverted)
Legal statusRx-only, Schedule II; used in physician-assisted death in some jurisdictions under strict law
Last updated2026-09-12
Sources: DEA, FDA

Category comparison — Sedatives & Hypnotics

SubstanceClassTop risksStreet price
Pentobarbital (Nembutal)Schedule IIVeterinary euthanasia drug — overdose is usually fatal; Narrow safety margin (barbiturate)~$30–$100+ per vial/capsule-equivalent
Zolpidem (Ambien/Stilnox)Schedule IVSleep-walking, sleep-driving, hallucinations; Dependence and rebound insomnia~$2–$10 per 10 mg tablet
Secobarbital (Seconal)Schedule IIBarbiturates: tiny margin between dose and death; Fatal in overdose, brutal withdrawal (seizures) — replaced by benzos in medicine~$15–$40 per capsule where diverted
Carisoprodol (Soma)Schedule IVConverts to meprobamate (Miltown) — dependence; Popular 'Soma Coma' mix with opioids — deadly~$1–$8 per 350 mg tablet
Cyclobenzaprine (Flexeril)Not scheduledOverdose causes hallucinations, seizures, heart rhythm problems; Abuse usually in combination (potentiates opioids)~$1–$5 per 10 mg tablet
Butalbital (Fioricet/Fiorinal)Schedule IIIBarbiturate dependence — tolerance builds in weeks; Rebound headaches drive overuse~$2–$8 per tablet
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does Pentobarbital (Nembutal) look like?

Yellow capsules, pink injectable solution (veterinary), powder

What are the signs of a Pentobarbital (Nembutal) overdose?

Coma; Absent breathing; Pupils dilated then fixed Call emergency services immediately.

How addictive is it?

Veterinary euthanasia drug — overdose is usually fatal Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.