Peptides & Research Chemicals
PT-141 (Bremelanotide)
Street names: Bremelanotide, Vyleesi (Rx)
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Melanocortin-receptor libido drug — works on the brain, not blood flow
- Approved for hypoactive sexual desire in women
⚠Key risks
- Nausea is near-universal on dosing (the #1 side)
- Blood-pressure spikes then drops — the BP warning is real
- Darkening of moles/gums (melanocortin class effect)
- Grey-market vials: dosing guesswork
✚Overdose signs
- Severe nausea/vomiting
- Fainting (BP drop)
- Skin darkening changes
📋Quick facts
Also known asBremelanotide, Vyleesi (Rx)
CategoryPeptides & Research Chemicals
Schedule / classRx-only (US, approved 2019 as Vyleesi); grey peptides unscheduled
Appearance1.75–10 mg vials grey-market; Rx auto-injector pens
Street price~$20–$60 per vial grey-market
Legal statusRx-only as Vyleesi; grey 'research' supply unregulated
Last updated2026-09-16
Sources: FDA
Category comparison — Peptides & Research Chemicals
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| PT-141 (Bremelanotide) | Rx-only | Nausea is near-universal on dosing (the #1 side); Blood-pressure spikes then drops — the BP warning is real | ~$20–$60 per vial grey-market |
| Melanotan II | Unscheduled | Unapproved — regulators (FDA/TGA/MHRA) have issued warnings and seizures; 'Melanotan rage' — documented mood/aggression changes | ~$20–$50 per 10 mg vial grey-market |
| Sildenafil (Viagra) | Rx-only — not a controlled drug | THE most counterfeited drug class in the world — fake sildenafil is a leading fentanyl-pill channel in some regions; Dangerous blood-pressure drop with nitrates (heart meds) — potentially fatal combo | ~$1–$15 per tablet |
Street prices are regional estimates. Potency and cuts vary constantly.
RxBrand names on the grey market
These brands are sold as this compound. Same molecule, different label and supply chain — quality varies enormously between them.
PT-141
?Frequently asked questions
What does PT-141 (Bremelanotide) look like?
1.75–10 mg vials grey-market; Rx auto-injector pens
What are the signs of a PT-141 (Bremelanotide) overdose?
Severe nausea/vomiting; Fainting (BP drop); Skin darkening changes Call emergency services immediately.
How addictive is it?
Nausea is near-universal on dosing (the #1 side) Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.