Performance & Grey-Market Pharma
Yohimbine
Street names: Yohimbe, Yohimbine HCl, Aphrodyne
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Alpha-2 adrenergic blocker: energy, arousal, fat-mobilization — gym and sexual-stimulant markets
⚠Key risks
- ANXIETY SPIKES, panic attacks, racing heart, blood-pressure swings at supplement doses
- Bark extracts are wildly misdosed — some contain 10× the labeled alkaloid
- Banned in several countries as unapproved drug; EU restricted
- Dangerous with MAOIs, stimulants, or heart conditions
✚Overdose signs
- Racing heart, hypertension
- Tremor, anxiety, sweating
- Dizziness, fainting
📋Quick facts
Also known asYohimbe, Yohimbine HCl, Aphrodyne
CategoryPerformance & Grey-Market Pharma
Schedule / classRx drug (US, yohimbine HCl); supplement (yohimbe bark) unregulated
Appearance2–5 mg tablets; bark extract capsules (variable content)
Street price~$10–$30 per bottle supplements; Rx tabs $1–$3
Legal statusRx-only US (HCl); supplements in grey zone; restricted EU; banned Canada as unapproved
Last updated2026-09-18
Sources: FDA, EMCDDA, PubMed
Category comparison — Performance & Grey-Market Pharma
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Yohimbine | Rx drug | ANXIETY SPIKES, panic attacks, racing heart, blood-pressure swings at supplement doses; Bark extracts are wildly misdosed — some contain 10× the labeled alkaloid | ~$10–$30 per bottle supplements |
| Clenbuterol HCl | Not approved for human use | Racing heart, arrhythmia, tremors; Overdose: dangerous potassium shifts, cardiac events | ~$0.50–$2 per 40 mcg tablet |
| DMAA (1,3-Dimethylamylamine) | Illegal dietary supplement | LINKED TO DEATHS — heart attacks, strokes in young healthy users; soldiers died on DMAA supplements; Narrow safety margin — small overdose causes cardiac events | $30–$60 per pre-workout tub |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Yohimbine look like?
2–5 mg tablets; bark extract capsules (variable content)
What are the signs of a Yohimbine overdose?
Racing heart, hypertension; Tremor, anxiety, sweating; Dizziness, fainting Call emergency services immediately.
How addictive is it?
ANXIETY SPIKES, panic attacks, racing heart, blood-pressure swings at supplement doses Dependence can develop with regular use.