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Opioids

2-Methyl-AP-237

Street names: 2-M-AP-237, AP-237 analog

⚡What it does

  • AP-237 derivative with µ-opioid activity — sold as a 'legal opioid' RC

⚠Key risks

  • Part of the 2020s RC opioid wave filling gaps after nitazene scheduling
  • Respiratory depression standard
  • Unknown purity; often mixed with other RC opioids
  • Little human data

✚Overdose signs

  • Respiratory depression
  • Pinpoint pupils, sedation

Category comparison — Opioids

SubstanceClassTop risksStreet price
2-Methyl-AP-237Analogue prosecutionsPart of the 2020s RC opioid wave filling gaps after nitazene scheduling; Respiratory depression standard$25–$60/g
HeroinSchedule IExtremely addictive — physical dependence in weeks; Overdose: breathing slows or stops~$10–$40 per bag
FentanylSchedule IIRespiratory depression; Addiction in days~$20–$40 per counterfeit pill
Fentanyl HCl (powder)Schedule II / analogue prosecutionsLab-purity powder is far stronger than street mixes; Weighing errors are fatal~$60–$120/gram wholesale equivalent
AcetylfentanylSchedule I~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses~$25–$60/g where found
Furanylfentanyl (Fu-F)Schedule ILinked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl~$20–$50/g
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does 2-Methyl-AP-237 look like?

White/off-white powder; China-export RC opioid

What are the signs of a 2-Methyl-AP-237 overdose?

Respiratory depression; Pinpoint pupils, sedation Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.

How addictive is it?

Part of the 2020s RC opioid wave filling gaps after nitazene scheduling Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.