Opioids
2-Methyl-AP-237
Street names: 2-M-AP-237, AP-237 analog
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- AP-237 derivative with µ-opioid activity — sold as a 'legal opioid' RC
⚠Key risks
- Part of the 2020s RC opioid wave filling gaps after nitazene scheduling
- Respiratory depression standard
- Unknown purity; often mixed with other RC opioids
- Little human data
✚Overdose signs
- Respiratory depression
- Pinpoint pupils, sedation
📋Quick facts
Also known as2-M-AP-237, AP-237 analog
CategoryOpioids
Schedule / classAnalogue prosecutions (US); controlled several EU
AppearanceWhite/off-white powder; China-export RC opioid
Street price$25–$60/g
Legal statusAnalogue US; scheduled several EU; China export controls tightened
Last updated2026-09-18
Sources: EMCDDA, NPS-AD
Category comparison — Opioids
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| 2-Methyl-AP-237 | Analogue prosecutions | Part of the 2020s RC opioid wave filling gaps after nitazene scheduling; Respiratory depression standard | $25–$60/g |
| U-47700 (Pink / U4) | Schedule I | Linked to multiple DEATHS before scheduling — the drug behind the 2016 'pink' overdose wave; Potency ~7× morphine | ~$20–$60/g grey-market |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does 2-Methyl-AP-237 look like?
White/off-white powder; China-export RC opioid
What are the signs of a 2-Methyl-AP-237 overdose?
Respiratory depression; Pinpoint pupils, sedation Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.
How addictive is it?
Part of the 2020s RC opioid wave filling gaps after nitazene scheduling Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.