Dissociatives
Arylcyclohexylamine RCs (3-HO-PCP, 3-MeO-PCE, DCK, O-PCE)
Street names: 3-HO-PCP, 3-MeO-PCE, DCK, Deschloroketamine, O-PCE, 2-Oxo-PCE
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- PCP/ketamine-family dissociation: 3-HO-PCP is potent and long (heavy mania risk); DCK/O-PCE are MXE-style warmth
⚠Key risks
- MANIA + dangerous disinhibition (3-HO-PCP especially): users hurt themselves while detached
- Functional dissociation — appear sober, drive impaired
- Bladder toxicity class-wide with heavy use
- Compulsive redosing
- Little human data per compound
✚Overdose signs
- Catatonic unresponsiveness
- Severe agitation, mania
- Hypertension
📋Quick facts
Also known as3-HO-PCP, 3-MeO-PCE, DCK, Deschloroketamine, O-PCE, 2-Oxo-PCE
CategoryDissociatives
Schedule / classAnalogue prosecutions (US); controlled several EU/UK-PSA
AppearanceWhite/off-white crystalline powders
Street price~$25–$60/g
Legal statusAnalogue Act US; Class B UK (PSA); scheduled several EU
Last updated2026-09-18
Sources: EMCDDA, NPS-AD, TripSit
Category comparison — Dissociatives
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Arylcyclohexylamine RCs (3-HO-PCP, 3-MeO-PCE, DCK, O-PCE) | Analogue prosecutions | MANIA + dangerous disinhibition (3-HO-PCP especially): users hurt themselves while detached; Functional dissociation — appear sober, drive impaired | ~$25–$60/g |
| 3-MeO-PCP | Analog prosecution | MANIA and dangerous disinhibition — users hurt themselves/others; Overdose: severe dissociation, catatonia | ~$20–$50/g |
| Ketamine | Schedule III | Bladder damage (ketamine cystitis) with regular use; K-holes and accidents while impaired | ~$20–$60 per gram |
| Methoxetamine (MXE) | Analogue prosecutions | The original MXE wave showed bladder harm, dependence, and dissociative-panic hospitalizations; Banned nearly everywhere by 2016 — remaining supply is grey/unknown | Residual |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Arylcyclohexylamine RCs (3-HO-PCP, 3-MeO-PCE, DCK, O-PCE) look like?
White/off-white crystalline powders
What are the signs of a Arylcyclohexylamine RCs (3-HO-PCP, 3-MeO-PCE, DCK, O-PCE) overdose?
Catatonic unresponsiveness; Severe agitation, mania; Hypertension Call emergency services immediately.
How addictive is it?
MANIA + dangerous disinhibition (3-HO-PCP especially): users hurt themselves while detached Dependence can develop with regular use.