Bupropion (Wellbutrin / Zyban)
Street names: Wellbutrin, Zyban, Budeprion, 'Poor man's cocaine'
⚡What it does
- NDRI antidepressant — norepinephrine-dopamine reuptake blocker; energizing, activating, pro-focus at prescribed doses
- Smoking-cessation aid (Zyban) — cuts cravings and withdrawal
- At high doses: stimulant-like euphoria, talkativeness and energy — the 'poor man's cocaine' label comes from crushing and snorting 300+ mg
⚠Key risks
- Seizure risk is dose-dependent and real — crushing XR tablets or exceeding ~450 mg/day sharply raises the odds; injecting dissolved pills is seizure-and-infection roulette
- The 'stimulant' effect tempts mixing with alcohol, benzos or opioids — combination queries are enormous because users are trying to chase or soften the edges
- Anxiety, insomnia and blood-pressure spikes at recreational doses; the crash includes irritability and low mood
- Contraindicated with seizure disorders and eating disorders — recreational dosing ignores both screens
- XR tablets are designed to release slowly; defeating the matrix dumps the full daily dose at once
✚Overdose signs
- Seizure — the signature bupropion overdose event, can occur hours after ingestion
- Hallucinations, agitation, rapid heart rate and high blood pressure
- Fever and muscle rigidity in severe toxicity — emergency department territory
Category comparison — Stimulants
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Bupropion (Wellbutrin / Zyban) | Rx-only | Seizure risk is dose-dependent and real — crushing XR tablets or exceeding ~450 mg/day sharply raises the odds; injecting dissolved pills is seizure-and-infection roulette; The 'stimulant' effect tempts mixing with alcohol, benzos or opioids — combination queries are enormous because users are trying to chase or soften the edges | Cheap where diverted: ~$1–5 per 150 mg tablet |
| Cocaine | Schedule II | Heart attack/stroke even in young users; Severe addiction — craving cycle | ~$60–$120 per gram |
| Speed (amphetamine paste) | Schedule II | Insomnia, anxiety, paranoia; Heart strain and overheating | ~$10–$40 per gram |
| Methamphetamine | Schedule II | Addiction — among the most addictive drugs known; Meth mouth, skin sores, psychosis | ~$20–$100 per gram |
| Adderall (amphetamine salts) | Schedule II | Dependence and tolerance; Cardiovascular strain | ~$3–$15 per 30 mg tablet |
| Adderall XR | Schedule II | Same as Adderall; long duration masks sleep debt; Beads snorted bypass XR mechanism | ~$5–$20 per 30 mg capsule |
?Frequently asked questions
What does Bupropion (Wellbutrin / Zyban) look like?
75/100/150/300 mg tablets (immediate and extended release); abused by insufflation or injection of crushed pills
What are the signs of a Bupropion (Wellbutrin / Zyban) overdose?
Seizure — the signature bupropion overdose event, can occur hours after ingestion; Hallucinations, agitation, rapid heart rate and high blood pressure; Fever and muscle rigidity in severe toxicity — emergency department territory Call emergency services immediately.
How addictive is it?
Seizure risk is dose-dependent and real — crushing XR tablets or exceeding ~450 mg/day sharply raises the odds; injecting dissolved pills is seizure-and-infection roulette Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.