Sedatives & Hypnotics
Etomidate
Street names: Amidate, Hypnomidate, Etomidate-laced vapes
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Imidazole sedative-hypnotic — rapid unconsciousness, short duration
- No analgesia; amnesia at sub-anaesthetic doses
⚠Key risks
- UNODC EWA flags the RISE OF ETOMIDATE ANALOGUES (metomidate, propoxate) in street vapes 2024+
- Repeated use suppresses the adrenal glands — cortisol crisis risk
- Extremely addictive in the vape format — short-acting hypnotics hook fast
- Overdose = respiratory depression without opioid reversal tools
✚Overdose signs
- Unresponsiveness
- Slowed breathing
- Blue lips, hypotension
Category comparison — Sedatives & Hypnotics
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Etomidate | Rx-only surgical agent | UNODC EWA flags the RISE OF ETOMIDATE ANALOGUES (metomidate, propoxate) in street vapes 2024+; Repeated use suppresses the adrenal glands — cortisol crisis risk | Surgical ampoule diversion |
| Zolpidem (Ambien/Stilnox) | Schedule IV | Sleep-walking, sleep-driving, hallucinations; Dependence and rebound insomnia | ~$2–$10 per 10 mg tablet |
| Secobarbital (Seconal) | Schedule II | Barbiturates: tiny margin between dose and death; Fatal in overdose, brutal withdrawal (seizures) — replaced by benzos in medicine | ~$15–$40 per capsule where diverted |
| Carisoprodol (Soma) | Schedule IV | Converts to meprobamate (Miltown) — dependence; Popular 'Soma Coma' mix with opioids — deadly | ~$1–$8 per 350 mg tablet |
| Cyclobenzaprine (Flexeril) | Not scheduled | Overdose causes hallucinations, seizures, heart rhythm problems; Abuse usually in combination (potentiates opioids) | ~$1–$5 per 10 mg tablet |
| Pentobarbital (Nembutal) | Schedule II | Veterinary euthanasia drug — overdose is usually fatal; Narrow safety margin (barbiturate) | ~$30–$100+ per vial/capsule-equivalent |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Etomidate look like?
Clear liquid ampoules (surgical); increasingly detected in vape carts and 'knockout' products 2024+
What are the signs of a Etomidate overdose?
Unresponsiveness; Slowed breathing; Blue lips, hypotension Call emergency services immediately.
How addictive is it?
UNODC EWA flags the RISE OF ETOMIDATE ANALOGUES (metomidate, propoxate) in street vapes 2024+ Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.