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E
Opioids

Etonitazene

Street names: Etazene, EZ

Etonitazene — White/yellow/off-white powder, pills, or e-liquid for vaping

What it does

  • Intense opioid euphoria at microgram doses

Key risks

  • ~10–25× fentanyl potency
  • Active at sub-milligram doses — nearly impossible to dose safely

Overdose signs

  • Immediate respiratory depression
  • Unresponsiveness
  • Pinpoint pupils

📋Quick facts

Also known asEtazene, EZ
CategoryOpioids
Schedule / classSchedule I (US, 2023)
AppearanceWhite/yellow/off-white powder, pills, or e-liquid for vaping
Street price~$40–$100/g (equivalent to millions of doses)
Legal statusSchedule I (US, 2023); controlled/prohibited in EU, UK, Canada, Australia
Last updated2026-09-12
Sources: DEA, EMCDDA, WHO-UNODC

Category comparison — Opioids

SubstanceClassTop risksStreet price
EtonitazeneSchedule I~10–25× fentanyl potency; Active at sub-milligram doses — nearly impossible to dose safely~$40–$100/g
IsotodesnitazeneEmerging — prosecuted as analogueFentanyl-level or greater potency; Driving a new wave of overdose clusters since 2022~$30–$70/g where found
FentanylSchedule IIRespiratory depression; Addiction in days~$20–$40 per counterfeit pill
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does Etonitazene look like?

White/yellow/off-white powder, pills, or e-liquid for vaping

What are the signs of a Etonitazene overdose?

Immediate respiratory depression; Unresponsiveness; Pinpoint pupils Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.

How addictive is it?

~10–25× fentanyl potency Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.