Opioids
Isotodesnitazene
Street names: Iso, ISO
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Euphoria, heavy sedation — nitazene-class opioid
⚠Key risks
- Fentanyl-level or greater potency
- Driving a new wave of overdose clusters since 2022
✚Overdose signs
- Pinpoint pupils
- Slow breathing
- Blue lips
Category comparison — Opioids
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Isotodesnitazene | Emerging — prosecuted as analogue | Fentanyl-level or greater potency; Driving a new wave of overdose clusters since 2022 | ~$30–$70/g where found |
| Heroin | Schedule I | Extremely addictive — physical dependence in weeks; Overdose: breathing slows or stops | ~$10–$40 per bag |
| Fentanyl | Schedule II | Respiratory depression; Addiction in days | ~$20–$40 per counterfeit pill |
| Fentanyl HCl (powder) | Schedule II / analogue prosecutions | Lab-purity powder is far stronger than street mixes; Weighing errors are fatal | ~$60–$120/gram wholesale equivalent |
| Acetylfentanyl | Schedule I | ~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses | ~$25–$60/g where found |
| Furanylfentanyl (Fu-F) | Schedule I | Linked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl | ~$20–$50/g |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Isotodesnitazene look like?
White/yellow powder, often mixed into heroin or counterfeit pills
What are the signs of a Isotodesnitazene overdose?
Pinpoint pupils; Slow breathing; Blue lips Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.
How addictive is it?
Fentanyl-level or greater potency Dependence can develop with regular use.