Performance & Grey-Market Pharma
Isotretinoin (Accutane)
Street names: Accutane, Roaccutane, Isotroin
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- The definitive cystic-acne cure — shrinks sebaceous glands permanently
- Often lifelong clearance after one course
⚠Key risks
- TERATOGENIC — severe birth defects; pregnancy tests + two contraception forms required
- Dry skin/lips/eyes (universal)
- Depression/suicidality association — debated but monitored
- Grey-market acne 'brands' skip the monitoring that makes it safe
✚Overdose signs
- No acute overdose
- Severe headache, vision changes (pseudotumor cerebri — emergency)
- Mood crisis
📋Quick facts
Also known asAccutane, Roaccutane, Isotroin
CategoryPerformance & Grey-Market Pharma
Schedule / classRx-only with strict pregnancy-prevention programs (iPLEDGE US)
Appearance10/20/40 mg soft capsules; many generic brands
Street price~$0.50–$2 per capsule grey-market (pharmacy $100s/course)
Legal statusRx-only, pregnancy-category-X protocols; grey market skips safeguards
Last updated2026-09-16
Sources: FDA, EMA
Category comparison — Performance & Grey-Market Pharma
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Isotretinoin (Accutane) | Rx-only with strict pregnancy-prevention programs | TERATOGENIC — severe birth defects; pregnancy tests + two contraception forms required; Dry skin/lips/eyes (universal) | ~$0.50–$2 per capsule grey-market |
| Finasteride (Propecia/Proscar) | Rx-only — not controlled | Post-finasteride syndrome reports — persistent sexual dysfunction, depression, brain fog in a subset of users (debated but documented); Must be taken daily; gains reverse within a year of stopping | ~$0.30–$2 per tablet |
Street prices are regional estimates. Potency and cuts vary constantly.
RxBrand names on the grey market
These brands are sold as this compound. Same molecule, different label and supply chain — quality varies enormously between them.
AccutaneIsotroinSotretTretiva
?Frequently asked questions
What does Isotretinoin (Accutane) look like?
10/20/40 mg soft capsules; many generic brands
What are the signs of a Isotretinoin (Accutane) overdose?
No acute overdose; Severe headache, vision changes (pseudotumor cerebri — emergency); Mood crisis Call emergency services immediately.
How addictive is it?
TERATOGENIC — severe birth defects; pregnancy tests + two contraception forms required Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.