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Psychedelics

Kambo (Frog Secretion)

Street names: Kambô, Sapo, Vacina do sapo, Phyllomedusa ceremony

⚡What it does

  • NOT psychedelic — an intense purge: 15–40 min of vomiting, sweating, flushing, heart racing, then clarity
  • Amazonian hunting-ritual origin; biohacker and wellness ceremony trend

⚠Key risks

  • DOCUMENTED DEATHS: cardiac events and severe dehydration at ceremonies (2019–2025 reports)
  • No medical screening at most circles — blood pressure, heart conditions undetected
  • Unregulated practitioners; 'clean' secretion claims unverifiable
  • Contradicts medications; dangerous with MAOIs and cardiac drugs
  • The purge CAN mask real emergencies — collapse is not 'purging'

✚Overdose signs

  • Collapse, unresponsive
  • Chest pain, arrhythmia
  • Dehydration shock

Category comparison — Psychedelics

SubstanceClassTop risksStreet price
Kambo (Frog Secretion)Not a controlled drug — unregulated ceremony productDOCUMENTED DEATHS: cardiac events and severe dehydration at ceremonies (2019–2025 reports); No medical screening at most circles — blood pressure, heart conditions undetectedCeremonies $50–$300 per session
DMT (dimethyltryptamine)Schedule IPsychological distress ('bad trips'); Dangerous behavior if unprepared~$20–$60 per 50–100 mg dose
Peyote (mescaline cactus)Schedule ISevere nausea/vomiting; Psychological distress~$10–$30 per button where sold
Mescaline powderSchedule IHeavy nausea at dose; Panic/psychosis in vulnerable users~$20–$60 per dose
2C-BSchedule IVery dose-sensitive — steep curve between fun and overwhelming; Panic attacks~$10–$30 per pill or ~$50–$120 per gram
4-AcO-DMT (psilacetin)Analogue prosecutionsSold as 'legal mushrooms' — buyers misjudge dose; Panic, risky behavior~$20–$50 per dose
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does Kambo (Frog Secretion) look like?

Burned dots on the skin; secretion of the giant leaf frog (Phyllomedusa bicolor) applied to open gates

What are the signs of a Kambo (Frog Secretion) overdose?

Collapse, unresponsive; Chest pain, arrhythmia; Dehydration shock Call emergency services immediately.

How addictive is it?

DOCUMENTED DEATHS: cardiac events and severe dehydration at ceremonies (2019–2025 reports) Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.