Psychedelics
Kambo (Frog Secretion)
Street names: Kambô, Sapo, Vacina do sapo, Phyllomedusa ceremony
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- NOT psychedelic — an intense purge: 15–40 min of vomiting, sweating, flushing, heart racing, then clarity
- Amazonian hunting-ritual origin; biohacker and wellness ceremony trend
⚠Key risks
- DOCUMENTED DEATHS: cardiac events and severe dehydration at ceremonies (2019–2025 reports)
- No medical screening at most circles — blood pressure, heart conditions undetected
- Unregulated practitioners; 'clean' secretion claims unverifiable
- Contradicts medications; dangerous with MAOIs and cardiac drugs
- The purge CAN mask real emergencies — collapse is not 'purging'
✚Overdose signs
- Collapse, unresponsive
- Chest pain, arrhythmia
- Dehydration shock
📋Quick facts
Also known asKambô, Sapo, Vacina do sapo, Phyllomedusa ceremony
CategoryPsychedelics
Schedule / classNot a controlled drug — unregulated ceremony product
AppearanceBurned dots on the skin; secretion of the giant leaf frog (Phyllomedusa bicolor) applied to open gates
Street priceCeremonies $50–$300 per session
Legal statusUnregulated most places; Brazil permits traditional use; import rules vary
Last updated2026-09-18
Sources: PubMed, Poison Control, EMCDDA
Category comparison — Psychedelics
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Kambo (Frog Secretion) | Not a controlled drug — unregulated ceremony product | DOCUMENTED DEATHS: cardiac events and severe dehydration at ceremonies (2019–2025 reports); No medical screening at most circles — blood pressure, heart conditions undetected | Ceremonies $50–$300 per session |
| Ayahuasca (The Brew) | Schedule I components | THE DEADLY COMBINATION: vine MAOIs + antidepressants (SSRIs/SNRIs/MAOIs) or MDMA = serotonin syndrome — deaths documented at retreats; Hypertensive crisis with tyramine-containing foods (aged cheese, cured meats) around ceremonies | Retreats $500–$3,500 per week |
| Ibogaine (Iboga) | Schedule I | CARDIAC DEATHS — the documented killer: QT-prolongation and arrhythmia; multiple clinic deaths, often without proper ECG screening; Deaths have occurred days AFTER treatment (delayed arrhythmia) | Clinics $3,000–$10,000 per treatment |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Kambo (Frog Secretion) look like?
Burned dots on the skin; secretion of the giant leaf frog (Phyllomedusa bicolor) applied to open gates
What are the signs of a Kambo (Frog Secretion) overdose?
Collapse, unresponsive; Chest pain, arrhythmia; Dehydration shock Call emergency services immediately.
How addictive is it?
DOCUMENTED DEATHS: cardiac events and severe dehydration at ceremonies (2019–2025 reports) Dependence can develop with regular use.