Hair Loss & Hormone Meds
Letrozole (Femara)
Street names: Femara, Letroz, Letroplex
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Strongest mainstream AI — ~98% estrogen suppression
- Rapid gyno reversal at high doses (off-label)
⚠Key risks
- Estrogen 'crash': crippling joint pain, depression, zero libido
- Bone density loss
- Overkill for most PCT — reserved for gyno emergencies
✚Overdose signs
- No acute overdose
- Severe joint pain
- Fatigue, hot flashes
📋Quick facts
Also known asFemara, Letroz, Letroplex
CategoryHair Loss & Hormone Meds
Schedule / classRx-only — not controlled
Appearance2.5 mg yellow film-coated tablets
Street price~$1–$4 per 2.5 mg tablet grey-market
Legal statusRx-only; heavily diverted for PCT
Last updated2026-09-16
Sources: FDA, EMA
Category comparison — Hair Loss & Hormone Meds
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Letrozole (Femara) | Rx-only — not controlled | Estrogen 'crash': crippling joint pain, depression, zero libido; Bone density loss | ~$1–$4 per 2.5 mg tablet grey-market |
| Exemestane (Aromasin) | Rx-only — not controlled | Joint pain, low-mood and libido crash if estrogen goes too low; Bone density loss with long use | ~$1–$3 per 25 mg tablet grey-market |
| Anastrozole (Arimidex) | Rx-only | Bone density loss, joint pain with long-term use; Crash estrogen too low → depression, libido loss | ~$2–$8 per 1 mg tablet |
| Tamoxifen (Nolvadex) | Rx-only — not controlled | Blood-clot risk (DVT/PE) — the serious one; Mood disturbance, hot flashes | ~$0.50–$2 per 20 mg tablet grey-market |
Street prices are regional estimates. Potency and cuts vary constantly.
RxBrand names on the grey market
These brands are sold as this compound. Same molecule, different label and supply chain — quality varies enormously between them.
FemaraLetrozLetroplexFertoletMamazol
?Frequently asked questions
What does Letrozole (Femara) look like?
2.5 mg yellow film-coated tablets
What are the signs of a Letrozole (Femara) overdose?
No acute overdose; Severe joint pain; Fatigue, hot flashes Call emergency services immediately.
How addictive is it?
Estrogen 'crash': crippling joint pain, depression, zero libido Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.