Cannabinoids
MDMB-4en-PINACA
Street names: MDMB-4en-PINACA, 4en-PINACA
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Extremely potent synthetic-cannabinoid intoxication
⚠Key risks
- The dominant EU street-spice molecule of the 2020s — mass-poisoning outbreaks
- Active at microgram-level doses
- Withdrawal and dependence now documented
✚Overdose signs
- Collapse, unresponsive
- Seizures
- Slow heartbeat, vomiting
Category comparison — Cannabinoids
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| MDMB-4en-PINACA | Schedule I | The dominant EU street-spice molecule of the 2020s — mass-poisoning outbreaks; Active at microgram-level doses | ~$10–$30 per spice pack or paper square |
| 4F-ADB | Schedule I | Associated with 'Spice zombies' — catatonia, seizures; Unpredictable potency sprayed unevenly | ~$5–$20 per gram of 'herbal blend' |
| 5F-ADB / 5F-ADBICA | Schedule I | Multiple deaths linked to 5F-ADB (the compound behind early 'zombie spice' outbreaks); Seizures, kidney injury | ~$5–$20 per gram of blend |
| JWH-250 | Schedule I | First-generation spice compound; contaminated batches caused outbreaks; Anxiety, tachycardia | ~$5–$15 per gram of blend |
| NM-2201 (CBL-2201) | Analogue prosecutions | Little human data; Severe anxiety, seizures reported | ~$5–$20 per gram of blend |
| Cannabis (Weed) | Schedule I | Anxiety, panic attacks, paranoia — especially high-THC strains and concentrates; Impaired memory, coordination and driving ability for hours | ~$10–$20 per gram flower |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does MDMB-4en-PINACA look like?
Current-generation spice chemical sprayed on plant material and paper
What are the signs of a MDMB-4en-PINACA overdose?
Collapse, unresponsive; Seizures; Slow heartbeat, vomiting Call emergency services immediately.
How addictive is it?
The dominant EU street-spice molecule of the 2020s — mass-poisoning outbreaks Dependence can develop with regular use.