Opioids
Medetomidine
Street names: Medeto, New tranq, Medetomidine dope
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Profound, hours-long sedation and blackout
- Very slow heart rate and breathing; severe drops in blood pressure
- In someone opioid-dependent: precipitated, violent withdrawal on top of opioid withdrawal
⚠Key risks
- Not an opioid — naloxone does NOT reverse it, and it still shuts down breathing
- The successor to xylazine: detected in 18+ US states and roughly a third of tested opioid samples by late 2025
- Withdrawal is ICU-grade — severe hypertension, racing heart, agitation — and standard opioid-withdrawal treatment (clonidine protocols) often fails
- Wounds and tissue damage like xylazine's are being reported
✚Overdose signs
- Unresponsive with slow or gasping breathing
- Pinpoint pupils plus bradycardia (slow pulse) — a mixed picture that confuses responders
- Blue-gray lips and extremities
Category comparison — Opioids
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Medetomidine | Not federally scheduled | Not an opioid — naloxone does NOT reverse it, and it still shuts down breathing; The successor to xylazine: detected in 18+ US states and roughly a third of tested opioid samples by late 2025 | Sold as part of fentanyl/heroin bags |
| Heroin | Schedule I | Extremely addictive — physical dependence in weeks; Overdose: breathing slows or stops | ~$10–$40 per bag |
| Fentanyl | Schedule II | Respiratory depression; Addiction in days | ~$20–$40 per counterfeit pill |
| Fentanyl HCl (powder) | Schedule II / analogue prosecutions | Lab-purity powder is far stronger than street mixes; Weighing errors are fatal | ~$60–$120/gram wholesale equivalent |
| Acetylfentanyl | Schedule I | ~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses | ~$25–$60/g where found |
| Furanylfentanyl (Fu-F) | Schedule I | Linked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl | ~$20–$50/g |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Medetomidine look like?
No street form of its own — detected as a whitish powder mixed into fentanyl/heroin, often alongside xylazine and BTMPS
What are the signs of a Medetomidine overdose?
Unresponsive with slow or gasping breathing; Pinpoint pupils plus bradycardia (slow pulse) — a mixed picture that confuses responders; Blue-gray lips and extremities Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.
How addictive is it?
Not an opioid — naloxone does NOT reverse it, and it still shuts down breathing Dependence can develop with regular use.