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Weight Loss & Metabolic Meds

Metformin

Street names: Glucophage, Glycomet, Okamet, Fortamet

⚡What it does

  • First-line diabetes drug — improves insulin sensitivity
  • Modest weight loss, PCOS use
  • Biohacking interest: longevity claims (TAME trial)

⚠Key risks

  • GI upset (diarrhea, nausea) — titrate slowly
  • Lactic acidosis — rare, dangerous, mostly in kidney disease
  • B12 deficiency with long use
  • Cheap and rarely faked — one of the safer grey buys

✚Overdose signs

  • No acute overdose
  • Severe fatigue, breathing trouble (lactic acidosis) — emergency

Category comparison — Weight Loss & Metabolic Meds

SubstanceClassTop risksStreet price
MetforminRx-only — not controlledGI upset (diarrhea, nausea) — titrate slowly; Lactic acidosis — rare, dangerous, mostly in kidney disease~$0.05–$0.30 per tablet
Liothyronine (T3)Rx-only — not controlledAt abuse doses: cardiac arrhythmia, heart failure, bone loss; Muscle catabolism — the 'cut' comes with your muscle~$0.50–$2 per tablet grey-market
Levothyroxine (T4)Rx-only — not controlledOvertreatment = hyperthyroid state: palpitations, anxiety, bone loss; Taking it without hypothyroidism provides little benefit at real risk~$0.10–$0.50 per tablet
Orlistat (Xenical/Alli)OTCOily stools, urgency, flatulence — the famous GI sides if you eat fatty; Fat-soluble vitamin absorption drops (take a multivitamin)~$0.50–$2 per capsule
Sibutramine (Meridia)WithdrawnWITHDRAWN worldwide for cardiovascular events (strokes, heart attacks in the SCOUT trial); Survives in adulterated supplements — buyers don't know they're taking it~$0.50–$2 per capsule illicit
L-CarnitineSupplement — unregulatedTMAO production — potential cardiovascular concern with chronic high dose; Injectable forms: infection risk, zero benefit over oral~$10–$30/month supplement
Street prices are regional estimates. Potency and cuts vary constantly.

RxBrand names on the grey market

These brands are sold as this compound. Same molecule, different label and supply chain — quality varies enormously between them.

MetforGlycomet SROkamet

?Frequently asked questions

What does Metformin look like?

500/850/1000 mg tablets; XR versions

What are the signs of a Metformin overdose?

No acute overdose; Severe fatigue, breathing trouble (lactic acidosis) — emergency Call emergency services immediately.

How addictive is it?

GI upset (diarrhea, nausea) — titrate slowly Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.