Opioids
N-Desethyl Protonitazene
Street names: Desethyl proto, Norprotonitazene
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Protonitazene metabolite/analogue — active opioid
- Potency near fentanyl class
⚠Key risks
- Notified to EU EWS 2024 — detected as both a metabolite and a marketed RC
- Presence complicates toxicology: 'protonitazene' deaths may involve this more potent variant
- No human safety data
- Survives some immunoassays
✚Overdose signs
- Respiratory depression
- Deep sedation
- Bradycardia + hypotension
Category comparison — Opioids
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| N-Desethyl Protonitazene | Not scheduled | Notified to EU EWS 2024 — detected as both a metabolite and a marketed RC; Presence complicates toxicology: 'protonitazene' deaths may involve this more potent variant | RC-market pricing |
| Heroin | Schedule I | Extremely addictive — physical dependence in weeks; Overdose: breathing slows or stops | ~$10–$40 per bag |
| Fentanyl | Schedule II | Respiratory depression; Addiction in days | ~$20–$40 per counterfeit pill |
| Fentanyl HCl (powder) | Schedule II / analogue prosecutions | Lab-purity powder is far stronger than street mixes; Weighing errors are fatal | ~$60–$120/gram wholesale equivalent |
| Acetylfentanyl | Schedule I | ~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses | ~$25–$60/g where found |
| Furanylfentanyl (Fu-F) | Schedule I | Linked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl | ~$20–$50/g |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does N-Desethyl Protonitazene look like?
Off-white powder; identified in post-mortem and seizure samples
What are the signs of a N-Desethyl Protonitazene overdose?
Respiratory depression; Deep sedation; Bradycardia + hypotension Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.
How addictive is it?
Notified to EU EWS 2024 — detected as both a metabolite and a marketed RC Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.