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C
Opioids

Codeine–Ibuprofen (Nurofen Plus) Abuse

Street names: Nurofen Plus, Co-codaprin, Co-codamol OTC variants

⚡What it does

  • Mild opioid euphoria and relaxation
  • Pain relief

⚠Key risks

  • High-dose abuse floods the body with ibuprofen — stomach bleeding, kidney failure
  • Gateway to stronger opioids for some users
  • Daily-codeine dependence develops quietly

✚Overdose signs

  • Stomach pain, black stools (GI bleed)
  • Slow breathing
  • Confusion, ringing ears

Category comparison — Opioids

SubstanceClassTop risksStreet price
Codeine–Ibuprofen (Nurofen Plus) AbuseOTCHigh-dose abuse floods the body with ibuprofen — stomach bleeding, kidney failure; Gateway to stronger opioids for some users~$8–$15 per pack OTC
HeroinSchedule IExtremely addictive — physical dependence in weeks; Overdose: breathing slows or stops~$10–$40 per bag
FentanylSchedule IIRespiratory depression; Addiction in days~$20–$40 per counterfeit pill
Fentanyl HCl (powder)Schedule II / analogue prosecutionsLab-purity powder is far stronger than street mixes; Weighing errors are fatal~$60–$120/gram wholesale equivalent
AcetylfentanylSchedule I~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses~$25–$60/g where found
Furanylfentanyl (Fu-F)Schedule ILinked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl~$20–$50/g
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does Codeine–Ibuprofen (Nurofen Plus) Abuse look like?

Over-the-counter combination tablets (codeine 12.8 mg + ibuprofen 200 mg)

What are the signs of a Codeine–Ibuprofen (Nurofen Plus) Abuse overdose?

Stomach pain, black stools (GI bleed); Slow breathing; Confusion, ringing ears Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.

How addictive is it?

High-dose abuse floods the body with ibuprofen — stomach bleeding, kidney failure Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.