Weight Loss & Metabolic Meds
Orlistat (Xenical/Alli)
Street names: Xenical, Alli, Orligal
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Blocks ~30% of dietary fat absorption (lipase inhibitor)
- Modest but real weight loss with diet
⚠Key risks
- Oily stools, urgency, flatulence — the famous GI sides if you eat fatty
- Fat-soluble vitamin absorption drops (take a multivitamin)
- Rare severe liver injury reports
- Grey-market 120 mg 'Xenical' often fake
✚Overdose signs
- No acute overdose
- Severe GI distress
- Signs of liver trouble (rare)
📋Quick facts
Also known asXenical, Alli, Orligal
CategoryWeight Loss & Metabolic Meds
Schedule / classOTC (60 mg, Alli) / Rx (120 mg) — not controlled
AppearanceBlue/white 60/120 mg capsules
Street price~$0.50–$2 per capsule; Alli OTC ~$50/box
Legal statusOTC low-dose / Rx high-dose; counterfeits widespread
Last updated2026-09-16
Sources: FDA, EMA
Category comparison — Weight Loss & Metabolic Meds
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Orlistat (Xenical/Alli) | OTC | Oily stools, urgency, flatulence — the famous GI sides if you eat fatty; Fat-soluble vitamin absorption drops (take a multivitamin) | ~$0.50–$2 per capsule |
| Sibutramine (Meridia) | Withdrawn | WITHDRAWN worldwide for cardiovascular events (strokes, heart attacks in the SCOUT trial); Survives in adulterated supplements — buyers don't know they're taking it | ~$0.50–$2 per capsule illicit |
| Metformin | Rx-only — not controlled | GI upset (diarrhea, nausea) — titrate slowly; Lactic acidosis — rare, dangerous, mostly in kidney disease | ~$0.05–$0.30 per tablet |
Street prices are regional estimates. Potency and cuts vary constantly.
RxBrand names on the grey market
These brands are sold as this compound. Same molecule, different label and supply chain — quality varies enormously between them.
OrlistatOrligalXenical
?Frequently asked questions
What does Orlistat (Xenical/Alli) look like?
Blue/white 60/120 mg capsules
What are the signs of a Orlistat (Xenical/Alli) overdose?
No acute overdose; Severe GI distress; Signs of liver trouble (rare) Call emergency services immediately.
How addictive is it?
Oily stools, urgency, flatulence — the famous GI sides if you eat fatty Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.