Overdose or emergency? Call now Hotlines · US 911 · UK 999 · EU 112 · AU 000 · IN 112 · 988 (US crisis) Hotlines
P
Opioids

Para-fluorofentanyl (4-FBF)

Street names: pFF, 4-FBF, Fluorofentanyl

⚡What it does

  • Fentanyl-family opioid — same warmth, sedation and euphoria, typically described as slightly longer-acting than fentanyl itself
  • Roughly comparable overdose potency to fentanyl by weight; effects outlast the initial rush
  • Same instant dependence pattern: tolerance within days, withdrawal within weeks

⚠Key risks

  • The most-reported fentanyl analogue in DEA forensic casework — when a seizure report says 'fentanyl analogue,' this is often the molecule
  • Presence in cocaine supplies means stimulant users with zero opioid tolerance are overdosing without ever choosing an opioid
  • Naloxone reverses it, but long-acting analogues can re-sedate after naloxone wears off — stay with the person until help arrives
  • Pressed 'oxy 30s' containing pFF instead of oxycodone have killed people who thought they were taking a known dose
  • Same adulterant trajectory: dealers mix it with xylazine, medetomidine and cutting agents like BTMPS

✚Overdose signs

  • Unrousable, slow or absent breathing
  • Blue lips or fingertips; cold, clammy skin
  • Gurgling or snoring sounds — naloxone now, rescue breathing, emergency call

Category comparison — Opioids

SubstanceClassTop risksStreet price
Para-fluorofentanyl (4-FBF)Schedule IThe most-reported fentanyl analogue in DEA forensic casework — when a seizure report says 'fentanyl analogue,' this is often the molecule; Presence in cocaine supplies means stimulant users with zero opioid tolerance are overdosing without ever choosing an opioid~$15–40/g wholesale
HeroinSchedule IExtremely addictive — physical dependence in weeks; Overdose: breathing slows or stops~$10–$40 per bag
FentanylSchedule IIRespiratory depression; Addiction in days~$20–$40 per counterfeit pill
Fentanyl HCl (powder)Schedule II / analogue prosecutionsLab-purity powder is far stronger than street mixes; Weighing errors are fatal~$60–$120/gram wholesale equivalent
AcetylfentanylSchedule I~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses~$25–$60/g where found
Furanylfentanyl (Fu-F)Schedule ILinked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl~$20–$50/g
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does Para-fluorofentanyl (4-FBF) look like?

White to off-white powder; found loose, in fake oxycodone pills, and mixed into heroin and cocaine supplies

What are the signs of a Para-fluorofentanyl (4-FBF) overdose?

Unrousable, slow or absent breathing; Blue lips or fingertips; cold, clammy skin; Gurgling or snoring sounds — naloxone now, rescue breathing, emergency call Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.

How addictive is it?

The most-reported fentanyl analogue in DEA forensic casework — when a seizure report says 'fentanyl analogue,' this is often the molecule Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.