Peptides & Research Chemicals
PE 22-28
Street names: Laminin receptor peptide
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Marketed as a fast-acting antidepressant peptide (animal data)
- 'Kicks in within minutes' community claims
⚠Key risks
- No human trials
- Antidepressant-adjacent claims with zero dosing science
- Standard research-chemical risks
✚Overdose signs
- Unknown in humans
- Injection-site infection
Category comparison — Peptides & Research Chemicals
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| PE 22-28 | 'Research chemical' — no human approval | No human trials; Antidepressant-adjacent claims with zero dosing science | ~$25–$60 per vial grey-market |
| BPC-157 | Unscheduled — 'research chemical', not approved for human use anywhere | ZERO human clinical trials — all human use is anecdotal self-experimentation; Unregulated synthesis: purity, sterility, and actual content unverified | ~$20–$60 per 5 mg vial grey-market |
| TB-500 (Thymosin Beta-4 fragment) | Unscheduled — 'research chemical'; banned in sport | No approved human use or trials — same self-experimentation class as BPC-157; Growth/repair factor activity raises theoretical cancer concerns | ~$25–$70 per vial grey-market |
| Melanotan II | Unscheduled | Unapproved — regulators (FDA/TGA/MHRA) have issued warnings and seizures; 'Melanotan rage' — documented mood/aggression changes | ~$20–$50 per 10 mg vial grey-market |
| GHRPs & GH Secretagogues | Unscheduled — 'research chemicals' | All are 'research chemical' grade unless pharmacy-sourced: purity unknown; Water retention, carpal-tunnel symptoms, insulin resistance with chronic use | ~$15–$40 per vial grey-market |
| IGF-1 & MGF analogues | Unscheduled — 'research chemicals'; IGF-1 is Rx | Hypoglycemia — IGF-1 pulls blood sugar down hard; dangerous in diabetics; Theoretical but serious cancer concerns — IGF-1 feeds tumor growth | ~$30–$80 per vial grey-market |
Street prices are regional estimates. Potency and cuts vary constantly.
RxBrand names on the grey market
These brands are sold as this compound. Same molecule, different label and supply chain — quality varies enormously between them.
PE 22-28
?Frequently asked questions
What does PE 22-28 look like?
Lyophilized microgram vials
What are the signs of a PE 22-28 overdose?
Unknown in humans; Injection-site infection Call emergency services immediately.
How addictive is it?
No human trials Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.