Sedatives & Hypnotics
Trazodone (Desyrel)
Street names: Desyrel, Traz, Oleptro
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Sedating antidepressant — the classic off-label sleep prescription
- Antianxiety at low doses
⚠Key risks
- PRIAPISM — the famous side effect: painful erections lasting hours; untreated = permanent damage. Emergency if >4 h
- Orthostatic hypotension: falls, dizziness
- Serotonin syndrome in combination
- Dependence as a sleep crutch; withdrawal insomnia
✚Overdose signs
- Priapism (emergency)
- Severe dizziness, fainting
- Irregular heart rhythm
Category comparison — Sedatives & Hypnotics
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Trazodone (Desyrel) | Rx-only — not controlled | PRIAPISM — the famous side effect: painful erections lasting hours; untreated = permanent damage. Emergency if >4 h; Orthostatic hypotension: falls, dizziness | ~$0.20–$1 per tablet |
| Zolpidem (Ambien/Stilnox) | Schedule IV | Sleep-walking, sleep-driving, hallucinations; Dependence and rebound insomnia | ~$2–$10 per 10 mg tablet |
| Secobarbital (Seconal) | Schedule II | Barbiturates: tiny margin between dose and death; Fatal in overdose, brutal withdrawal (seizures) — replaced by benzos in medicine | ~$15–$40 per capsule where diverted |
| Carisoprodol (Soma) | Schedule IV | Converts to meprobamate (Miltown) — dependence; Popular 'Soma Coma' mix with opioids — deadly | ~$1–$8 per 350 mg tablet |
| Cyclobenzaprine (Flexeril) | Not scheduled | Overdose causes hallucinations, seizures, heart rhythm problems; Abuse usually in combination (potentiates opioids) | ~$1–$5 per 10 mg tablet |
| Pentobarbital (Nembutal) | Schedule II | Veterinary euthanasia drug — overdose is usually fatal; Narrow safety margin (barbiturate) | ~$30–$100+ per vial/capsule-equivalent |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Trazodone (Desyrel) look like?
50–300 mg tablets, white scored
What are the signs of a Trazodone (Desyrel) overdose?
Priapism (emergency); Severe dizziness, fainting; Irregular heart rhythm Call emergency services immediately.
How addictive is it?
PRIAPISM — the famous side effect: painful erections lasting hours; untreated = permanent damage. Emergency if >4 h Dependence can develop with regular use.