Disociativos
Esketamine (Spravato)
Street names: Spravato, S-ketamine, Esket
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- El S-enantiómero de la ketamina como antidepresivo: alivio rápido (horas-días) para la depresión resistente al tratamiento
- Disociación clínica supervisada por sesión
⚠Key risks
- Clínica-sólo por una razón: picos de BP, disociación que requiere monitoreo
- Responsabilidad por abuso/diversión: por eso está bloqueada por REMS
- Daño a la vejiga con el esquema de dosificación repetida (2x / semana de iniciación)
- Las reivindicaciones de la calle "S-isómero ketamina" - principalmente marketing
- No es una droga de fiesta; el mercado negro 'Spravato' es falso
✚Overdose signs
- Disociación severa / pánico
- Signos de crisis hipertensiva
- Sedation
Comparación de categoría — Disociativos
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Esketamine (Spravato) | Schedule III | Clinic-only for a reason: BP spikes, dissociation requiring monitoring; Abuse/diversion liability — that's why it's REMS-locked | Clinic course $4,700–$6,800 first month US |
| Ketamine | Schedule III | Bladder damage (ketamine cystitis) with regular use; K-holes and accidents while impaired | ~$20–$60 per gram |
| Ketalar (ketamine injection) | Schedule III | IV use raises infection and dependence risk; Bladder harm identical to powder use | ~$30–$100 per vial |
| 2F-DCK (2-fluorodeschloroketamine) | Analogue prosecutions | Very little human safety data; Bladder toxicity assumed similar to ketamine | ~$25–$60 per gram |
| DXM (Dextromethorphan / Robotripping) | OTC | Serotonin syndrome — DXM is serotonergic; DEADLY with SSRIs, MAOIs, MDMA; Liver damage — Coricidin contains chlorpheniramine (antihistamine) that's hepatotoxic at abuse doses | ~$5–$12 per bottle |
| 3-MeO-PCP | Analog prosecution | MANIA and dangerous disinhibition — users hurt themselves/others; Overdose: severe dissociation, catatonia | ~$20–$50/g |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Esketamine (Spravato) look like?
Dispositivos de pulverización intranasal de 28 mg o 56 mg; administrados sólo en clínica (programa REMS)
What are the signs of a Esketamine (Spravato) overdose?
Disociación severa / pánico; Signos de crisis hipertensiva; Sedation Call emergency services immediately.
How addictive is it?
Clínica-sólo por una razón: picos de BP, disociación que requiere monitoreo Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.