Weight Loss & Metabolic Meds
5-Amino-1MQ
Street names: 5-Amino-1MQ, NNMT inhibitor, 5A1MQ
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Blocks the NNMT enzyme — marketed for fat loss and endurance; human evidence is essentially zero
⚠Key risks
- No approved human trials — dosing is guesswork from rodent studies
- Sold injectable: infection and sterility risks
- Long-term effects completely unknown
✚Overdose signs
- Unknown — no human overdose data
- Injection-site reactions
- Reported: headache, nausea
Category comparison — Weight Loss & Metabolic Meds
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| 5-Amino-1MQ | Unscheduled research compound — not approved anywhere | No approved human trials — dosing is guesswork from rodent studies; Sold injectable: infection and sterility risks | ~$40–$100 per vial/bottle |
| Liothyronine (T3) | Rx-only — not controlled | At abuse doses: cardiac arrhythmia, heart failure, bone loss; Muscle catabolism — the 'cut' comes with your muscle | ~$0.50–$2 per tablet grey-market |
| Levothyroxine (T4) | Rx-only — not controlled | Overtreatment = hyperthyroid state: palpitations, anxiety, bone loss; Taking it without hypothyroidism provides little benefit at real risk | ~$0.10–$0.50 per tablet |
| Orlistat (Xenical/Alli) | OTC | Oily stools, urgency, flatulence — the famous GI sides if you eat fatty; Fat-soluble vitamin absorption drops (take a multivitamin) | ~$0.50–$2 per capsule |
| Sibutramine (Meridia) | Withdrawn | WITHDRAWN worldwide for cardiovascular events (strokes, heart attacks in the SCOUT trial); Survives in adulterated supplements — buyers don't know they're taking it | ~$0.50–$2 per capsule illicit |
| Metformin | Rx-only — not controlled | GI upset (diarrhea, nausea) — titrate slowly; Lactic acidosis — rare, dangerous, mostly in kidney disease | ~$0.05–$0.30 per tablet |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does 5-Amino-1MQ look like?
Capsules and injectables sold by peptide vendors for 'metabolic enhancement'
What are the signs of a 5-Amino-1MQ overdose?
Unknown — no human overdose data; Injection-site reactions; Reported: headache, nausea Call emergency services immediately.
How addictive is it?
No approved human trials — dosing is guesswork from rodent studies Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.