Psychedelics
5-MeO-DMT (Bufo / Toad Venom)
Street names: Bufo, Toad, The God Molecule, 5-MeO
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- 5–20 min COMPLETE dissolution: white light, ego death, 'becoming everything' — far stronger per mg than DMT
- Bufo retreats popular in Mexico/US
⚠Key risks
- RETREAT DEATHS: asphyxiation and aspiration — facilitators sometimes restrain or pour water on people mid-experience; several documented fatalities (2018–2025)
- NOT the same as DMT — bufotenin (5-HO) vs 5-MeO confusion matters; smoking raw toad secretions adds bufotenin load
- Deadly combined with MAOIs (harmalas/Syrian rue) — serotonin syndrome
- Psychological destabilization: panic, mania in the days after
- Toad populations stressed by 'milking'
✚Overdose signs
- Loss of consciousness with vomiting (aspiration risk)
- Panic/struggling during the peak
- Serotonin syndrome signs with MAOIs
Category comparison — Psychedelics
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| 5-MeO-DMT (Bufo / Toad Venom) | Schedule I | RETREAT DEATHS: asphyxiation and aspiration — facilitators sometimes restrain or pour water on people mid-experience; several documented fatalities (2018–2025); NOT the same as DMT — bufotenin (5-HO) vs 5-MeO confusion matters; smoking raw toad secretions adds bufotenin load | Retreat ceremonies $150–$500 per session |
| DMT (dimethyltryptamine) | Schedule I | Psychological distress ('bad trips'); Dangerous behavior if unprepared | ~$20–$60 per 50–100 mg dose |
| Peyote (mescaline cactus) | Schedule I | Severe nausea/vomiting; Psychological distress | ~$10–$30 per button where sold |
| Mescaline powder | Schedule I | Heavy nausea at dose; Panic/psychosis in vulnerable users | ~$20–$60 per dose |
| 2C-B | Schedule I | Very dose-sensitive — steep curve between fun and overwhelming; Panic attacks | ~$10–$30 per pill or ~$50–$120 per gram |
| 4-AcO-DMT (psilacetin) | Analogue prosecutions | Sold as 'legal mushrooms' — buyers misjudge dose; Panic, risky behavior | ~$20–$50 per dose |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does 5-MeO-DMT (Bufo / Toad Venom) look like?
White powder (synthetic or extracted from Sonoran Desert toad glands); smoked/vaporized 5–20 mg
What are the signs of a 5-MeO-DMT (Bufo / Toad Venom) overdose?
Loss of consciousness with vomiting (aspiration risk); Panic/struggling during the peak; Serotonin syndrome signs with MAOIs Call emergency services immediately.
How addictive is it?
RETREAT DEATHS: asphyxiation and aspiration — facilitators sometimes restrain or pour water on people mid-experience; several documented fatalities (2018–2025) Dependence can develop with regular use.