Psychedelics
Yopo / Cebil (Anadenanthera Snuffs)
Street names: Yopo, Cebil, Vilca, Cojoba, Syrian rue partner
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Short 30–60 min intense tryptamine snuff experience (bufotenin/5-MeO-DMT/DMT mix)
- Traditional Caribbean/South American shamanic use
⚠Key risks
- Syrian rue combination = MAOI — DEADLY with SSRIs and MDMA (serotonin syndrome)
- Severe nausea/pain at insufflation; mucosal damage from repeated snuffing
- Little modern safety data; traditional preparations were purified by skilled practitioners
- Bufotenin-loaded snuffs are harsh and unpredictable
✚Overdose signs
- Serotonin syndrome signs with MAOIs
- Severe vomiting, collapse
- Extreme cardiovascular stress
Category comparison — Psychedelics
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Yopo / Cebil (Anadenanthera Snuffs) | DMT/bufotenin controlled US; seeds legal to possess most places; Syrian rue | Syrian rue combination = MAOI — DEADLY with SSRIs and MDMA (serotonin syndrome); Severe nausea/pain at insufflation; mucosal damage from repeated snuffing | Seeds $10–$30 per 100 g |
| DMT (dimethyltryptamine) | Schedule I | Psychological distress ('bad trips'); Dangerous behavior if unprepared | ~$20–$60 per 50–100 mg dose |
| Peyote (mescaline cactus) | Schedule I | Severe nausea/vomiting; Psychological distress | ~$10–$30 per button where sold |
| Mescaline powder | Schedule I | Heavy nausea at dose; Panic/psychosis in vulnerable users | ~$20–$60 per dose |
| 2C-B | Schedule I | Very dose-sensitive — steep curve between fun and overwhelming; Panic attacks | ~$10–$30 per pill or ~$50–$120 per gram |
| 4-AcO-DMT (psilacetin) | Analogue prosecutions | Sold as 'legal mushrooms' — buyers misjudge dose; Panic, risky behavior | ~$20–$50 per dose |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Yopo / Cebil (Anadenanthera Snuffs) look like?
Toasted and ground seeds of Anadenanthera peregrina/colubrina, snuffed; combined with Syrian rue (Peganum harmala) in modern use
What are the signs of a Yopo / Cebil (Anadenanthera Snuffs) overdose?
Serotonin syndrome signs with MAOIs; Severe vomiting, collapse; Extreme cardiovascular stress Call emergency services immediately.
How addictive is it?
Syrian rue combination = MAOI — DEADLY with SSRIs and MDMA (serotonin syndrome) Dependence can develop with regular use.