Performance & Grey-Market Pharma
AICAR (Acadesine)
Street names: AICA ribonucleotide, GW501516's twin (grey market)
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- AMPK activator — increases endurance at cellular level (animal data only)
⚠Key risks
- No human safety data — cancer-risk flags in cell studies
- Sold as research chemical, zero quality control
✚Overdose signs
- Unknown in humans
- Potential hypoglycemia symptoms
Category comparison — Performance & Grey-Market Pharma
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| AICAR (Acadesine) | Unscheduled | No human safety data — cancer-risk flags in cell studies; Sold as research chemical, zero quality control | ~$50–$150 per gram |
| Clenbuterol HCl | Not approved for human use | Racing heart, arrhythmia, tremors; Overdose: dangerous potassium shifts, cardiac events | ~$0.50–$2 per 40 mcg tablet |
| Anastrozole (Arimidex) | Rx-only | Bone density loss, joint pain with long-term use; Crash estrogen too low → depression, libido loss | ~$2–$8 per 1 mg tablet |
| Liraglutide (Saxenda) | Rx-only — not a controlled drug | Sold grey-market at huge markups with counterfeit/refilled pens; Nausea, pancreatitis risk | ~$200–$500 per pen grey-market |
| Naltrexone–Bupropion (Contrave) | Rx-only — not controlled | Bupropion lowers seizure threshold; Misuse for stimulant-like effect is possible but weak | ~$1–$4 per tablet grey-market |
| Orforglipron (Foundayo) | Rx-only — not controlled; newly approved | Expect an immediate wave of counterfeit 'research' orforglipron — verify pharmacy accreditation; GI side effects, dehydration | Pending launch |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does AICAR (Acadesine) look like?
White powder, sold as 'exercise in a pill' grey-market research chemical
What are the signs of a AICAR (Acadesine) overdose?
Unknown in humans; Potential hypoglycemia symptoms Call emergency services immediately.
How addictive is it?
No human safety data — cancer-risk flags in cell studies Dependence can develop with regular use.