Sedatives & Hypnotics
Cyproheptadine (Periactin) for Weight Gain
Street names: cyproheptadine, Periactin, weight gain pills, peritol, apetamin ingredient
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Increased appetite within days
- Drowsiness (strong at first)
- Gradual weight gain with sustained use
⚠Key risks
- Heavy sedation, especially combined with alcohol
- Anticholinergic effects: dry mouth, blurred vision, urinary retention, confusion in older users
- Weight gained is mostly fat
- Dependence on the routine — appetite crashes when stopped
- Counterfeit syrups are widespread
✚Overdose signs
- Extreme drowsiness or agitation (paradoxical)
- Rapid heart rate
- Dry flushed skin
- Hallucinations
- Seizures in children
Category comparison — Sedatives & Hypnotics
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Cyproheptadine (Periactin) for Weight Gain | Prescription only | Heavy sedation, especially combined with alcohol; Anticholinergic effects: dry mouth, blurred vision, urinary retention, confusion in older users | Genuine tablets cost a few dollars |
| Zolpidem (Ambien/Stilnox) | Schedule IV | Sleep-walking, sleep-driving, hallucinations; Dependence and rebound insomnia | ~$2–$10 per 10 mg tablet |
| Secobarbital (Seconal) | Schedule II | Barbiturates: tiny margin between dose and death; Fatal in overdose, brutal withdrawal (seizures) — replaced by benzos in medicine | ~$15–$40 per capsule where diverted |
| Carisoprodol (Soma) | Schedule IV | Converts to meprobamate (Miltown) — dependence; Popular 'Soma Coma' mix with opioids — deadly | ~$1–$8 per 350 mg tablet |
| Cyclobenzaprine (Flexeril) | Not scheduled | Overdose causes hallucinations, seizures, heart rhythm problems; Abuse usually in combination (potentiates opioids) | ~$1–$5 per 10 mg tablet |
| Pentobarbital (Nembutal) | Schedule II | Veterinary euthanasia drug — overdose is usually fatal; Narrow safety margin (barbiturate) | ~$30–$100+ per vial/capsule-equivalent |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Cyproheptadine (Periactin) for Weight Gain look like?
Small tablets or syrup; an old antihistamine whose appetite-stimulating side effect drives an off-label weight-gain market.
What are the signs of a Cyproheptadine (Periactin) for Weight Gain overdose?
Extreme drowsiness or agitation (paradoxical); Rapid heart rate; Dry flushed skin Call emergency services immediately.
How addictive is it?
Heavy sedation, especially combined with alcohol Dependence can develop with regular use.