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Hair Loss & Hormone Meds

Megestrol Acetate (Megace) for Weight Gain

Street names: megestrol, Megace, megestrol acetate, megace ES

⚡What it does

  • Substantial appetite increase
  • Weight gain (largely fat, not muscle)
  • Fluid retention

⚠Key risks

  • Blood clots (DVT, pulmonary embolism) — a serious, documented risk
  • Adrenal suppression with long use
  • Fluid retention strains the heart
  • Increases fat mass rather than lean mass
  • Sometimes misused in bodybuilding and 'curves' communities

✚Overdose signs

  • Swollen painful leg (clot warning)
  • Shortness of breath (emergency — possible pulmonary embolism)
  • Sudden weight gain from fluid

Category comparison — Hair Loss & Hormone Meds

SubstanceClassTop risksStreet price
Megestrol Acetate (Megace) for Weight GainPrescription onlyBlood clots (DVT, pulmonary embolism) — a serious, documented risk; Adrenal suppression with long usePrescription-only
Somatropin (Human Growth Hormone)Rx-only; Schedule III/IV equivalent in most regionsCounterfeit rate near total — independent tests find most 'HGH' is hCG, IGF, or nothing; Real GH at abuse doses: insulin resistance, carpal tunnel, organ growth (acromegaly features)~$2–$10 per IU grey-market
Finasteride (Propecia/Proscar)Rx-only — not controlledPost-finasteride syndrome reports — persistent sexual dysfunction, depression, brain fog in a subset of users (debated but documented); Must be taken daily; gains reverse within a year of stopping~$0.30–$2 per tablet
Dutasteride (Avodart)Rx-only — not controlledSame post-finasteride-spectrum concerns, potentially stronger (broader 5-alpha-reduction blockade); Long half-life — weeks to clear; sides persist longer if they occur~$0.40–$2 per capsule grey-market generics
Exemestane (Aromasin)Rx-only — not controlledJoint pain, low-mood and libido crash if estrogen goes too low; Bone density loss with long use~$1–$3 per 25 mg tablet grey-market
Letrozole (Femara)Rx-only — not controlledEstrogen 'crash': crippling joint pain, depression, zero libido; Bone density loss~$1–$4 per 2.5 mg tablet grey-market
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does Megestrol Acetate (Megace) for Weight Gain look like?

Oral suspension or tablets; a synthetic progestin hormone approved to treat appetite loss and wasting in cancer and AIDS patients.

What are the signs of a Megestrol Acetate (Megace) for Weight Gain overdose?

Swollen painful leg (clot warning); Shortness of breath (emergency — possible pulmonary embolism); Sudden weight gain from fluid Call emergency services immediately.

How addictive is it?

Blood clots (DVT, pulmonary embolism) — a serious, documented risk Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.