Weight Loss & Metabolic Meds
Diethylpropion (Tenuate)
Street names: diethylpropion, Tenuate, amfepramone, Tenuate Dospan
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Appetite suppression
- Mild stimulation
- Short-term weight loss
⚠Key risks
- EU regulators withdrew it in 2000 over a poor risk-benefit balance
- Dependence
- Raised heart rate and blood pressure
- Insomnia and agitation
- Still prescribed in the US and Latin America
✚Overdose signs
- Severe agitation
- Chest pain
- High blood pressure
- Hallucinations
Category comparison — Weight Loss & Metabolic Meds
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Diethylpropion (Tenuate) | Schedule IV | EU regulators withdrew it in 2000 over a poor risk-benefit balance; Dependence | US prescription cost roughly $20-50/month generic |
| Liothyronine (T3) | Rx-only — not controlled | At abuse doses: cardiac arrhythmia, heart failure, bone loss; Muscle catabolism — the 'cut' comes with your muscle | ~$0.50–$2 per tablet grey-market |
| Levothyroxine (T4) | Rx-only — not controlled | Overtreatment = hyperthyroid state: palpitations, anxiety, bone loss; Taking it without hypothyroidism provides little benefit at real risk | ~$0.10–$0.50 per tablet |
| Orlistat (Xenical/Alli) | OTC | Oily stools, urgency, flatulence — the famous GI sides if you eat fatty; Fat-soluble vitamin absorption drops (take a multivitamin) | ~$0.50–$2 per capsule |
| Sibutramine (Meridia) | Withdrawn | WITHDRAWN worldwide for cardiovascular events (strokes, heart attacks in the SCOUT trial); Survives in adulterated supplements — buyers don't know they're taking it | ~$0.50–$2 per capsule illicit |
| Metformin | Rx-only — not controlled | GI upset (diarrhea, nausea) — titrate slowly; Lactic acidosis — rare, dangerous, mostly in kidney disease | ~$0.05–$0.30 per tablet |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Diethylpropion (Tenuate) look like?
White tablets or extended-release tablets; an amphetamine-type appetite suppressant.
What are the signs of a Diethylpropion (Tenuate) overdose?
Severe agitation; Chest pain; High blood pressure Call emergency services immediately.
How addictive is it?
EU regulators withdrew it in 2000 over a poor risk-benefit balance Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.