Opioids
Metonitazene
Street names: Metonitazene, Nitazene analog
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Nitazene-class opioid — fentanyl-level or greater potency, long duration
⚠Key risks
- Drove 2021 US east-coast overdose waves; detected in 'dope' and counterfeit pills
- Standard drug screens miss it — hospitals often don't know what reversed them
- Naloxone works, repeat doses needed
- Class: 1950s Ciba compounds never approved for a reason
✚Overdose signs
- Respiratory depression
- Unresponsive, cyanosis
- Re-sedation after naloxone wears off
📋Quick facts
Also known asMetonitazene, Nitazene analog
CategoryOpioids
Schedule / classSchedule I (US)
AppearanceYellow/tan/off-white powder, pressed pills
Street priceMixed into bags — no separate street price
Legal statusSchedule I US; controlled EU/UK
Last updated2026-09-18
Sources: DEA, EMCDDA, NIDA
Category comparison — Opioids
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Metonitazene | Schedule I | Drove 2021 US east-coast overdose waves; detected in 'dope' and counterfeit pills; Standard drug screens miss it — hospitals often don't know what reversed them | Mixed into bags — no separate street price |
| Etonitazene | Schedule I | ~10–25× fentanyl potency; Active at sub-milligram doses — nearly impossible to dose safely | ~$40–$100/g |
| Isotodesnitazene | Emerging — prosecuted as analogue | Fentanyl-level or greater potency; Driving a new wave of overdose clusters since 2022 | ~$30–$70/g where found |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Metonitazene look like?
Yellow/tan/off-white powder, pressed pills
What are the signs of a Metonitazene overdose?
Respiratory depression; Unresponsive, cyanosis; Re-sedation after naloxone wears off Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.
How addictive is it?
Drove 2021 US east-coast overdose waves; detected in 'dope' and counterfeit pills Dependence can develop with regular use.