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Opioids

o-Methylfentanyl (ortho-Methylfentanyl)

Street names: 2-methylfentanyl, ortho methyl fent, China White (sold as)

⚡What it does

  • Positional-isomer fentanyl — same opioid effects at similar potency
  • Sedation, euphoria, respiratory depression

⚠Key risks

  • Top US designer-opioid trend of 2025 (Aegis laboratory data)
  • Positional isomers can EVADE standard fentanyl immunoassays — a 'negative' strip does not clear it
  • Same 2-mg-lethal range as fentanyl
  • Drives cluster overdoses when it enters a pill supply

✚Overdose signs

  • Pinpoint pupils
  • Respiratory arrest
  • Cyanosis, limp body

Category comparison — Opioids

SubstanceClassTop risksStreet price
o-Methylfentanyl (ortho-Methylfentanyl)Schedule ITop US designer-opioid trend of 2025 (Aegis laboratory data); Positional isomers can EVADE standard fentanyl immunoassays — a 'negative' strip does not clear it~$20–40 per counterfeit pill
HeroinSchedule IExtremely addictive — physical dependence in weeks; Overdose: breathing slows or stops~$10–$40 per bag
FentanylSchedule IIRespiratory depression; Addiction in days~$20–$40 per counterfeit pill
Fentanyl HCl (powder)Schedule II / analogue prosecutionsLab-purity powder is far stronger than street mixes; Weighing errors are fatal~$60–$120/gram wholesale equivalent
AcetylfentanylSchedule I~5–15× weaker than fentanyl but still deadly at gram-level mistakes; Frequent cause of cluster overdoses~$25–$60/g where found
Furanylfentanyl (Fu-F)Schedule ILinked to hundreds of fatal overdoses 2016–2018; Potency similar to fentanyl~$20–$50/g
Street prices are regional estimates. Potency and cuts vary constantly.

?Frequently asked questions

What does o-Methylfentanyl (ortho-Methylfentanyl) look like?

White powder; pressed into counterfeit pills; sold as 'heroin' or 'fentanyl'

What are the signs of a o-Methylfentanyl (ortho-Methylfentanyl) overdose?

Pinpoint pupils; Respiratory arrest; Cyanosis, limp body Call emergency services immediately and give naloxone if available — it reverses opioid overdoses.

How addictive is it?

Top US designer-opioid trend of 2025 (Aegis laboratory data) Dependence can develop with regular use.

🔗Sources & further reading

Facts on this page are compiled from these primary sources. External links open in a new tab.