Weight Loss & Metabolic Meds
Rimonabant (Acomplia)
Street names: rimonabant, Acomplia, anti-munchies pill
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Reduced appetite and 'reward' response to food
- Modest weight loss
- Improved blood lipids
⚠Key risks
- Depression and suicidal ideation — the reason it was pulled
- Anxiety
- Nausea
- Never approved in the US
- Still found in counterfeit diet pills bought online
✚Overdose signs
- Severe nausea
- Agitation
- Mood deterioration requiring medical review
Category comparison — Weight Loss & Metabolic Meds
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| Rimonabant (Acomplia) | Withdrawn | Depression and suicidal ideation — the reason it was pulled; Anxiety | Counterfeit 'Acomplia' circulates on diet-pill websites |
| Liothyronine (T3) | Rx-only — not controlled | At abuse doses: cardiac arrhythmia, heart failure, bone loss; Muscle catabolism — the 'cut' comes with your muscle | ~$0.50–$2 per tablet grey-market |
| Levothyroxine (T4) | Rx-only — not controlled | Overtreatment = hyperthyroid state: palpitations, anxiety, bone loss; Taking it without hypothyroidism provides little benefit at real risk | ~$0.10–$0.50 per tablet |
| Orlistat (Xenical/Alli) | OTC | Oily stools, urgency, flatulence — the famous GI sides if you eat fatty; Fat-soluble vitamin absorption drops (take a multivitamin) | ~$0.50–$2 per capsule |
| Sibutramine (Meridia) | Withdrawn | WITHDRAWN worldwide for cardiovascular events (strokes, heart attacks in the SCOUT trial); Survives in adulterated supplements — buyers don't know they're taking it | ~$0.50–$2 per capsule illicit |
| Metformin | Rx-only — not controlled | GI upset (diarrhea, nausea) — titrate slowly; Lactic acidosis — rare, dangerous, mostly in kidney disease | ~$0.05–$0.30 per tablet |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does Rimonabant (Acomplia) look like?
Film-coated tablet; a CB1 cannabinoid receptor blocker — effectively the opposite of cannabis.
What are the signs of a Rimonabant (Acomplia) overdose?
Severe nausea; Agitation; Mood deterioration requiring medical review Call emergency services immediately.
How addictive is it?
Depression and suicidal ideation — the reason it was pulled Dependence can develop with regular use.
🔗Sources & further reading
Facts on this page are compiled from these primary sources. External links open in a new tab.