Rendimiento y farmacia gris
St John's Wort (Hypericum)
Street names: SJW, Hypericum perforatum, Amber, Klamath weed
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Efecto antidepresivo leve para la depresión leve a moderada (traducción alemana Rx)
- El psicoanálisis más estudiado
⚠Key risks
- REY DE LA INTERACCIÓN: induce CYP3A4 y P-gp – debilita los anticonceptivos orales (embarazos documentados), los antirretrovirales del VIH, los inmunosupresores de trasplante, los diluidores de la sangre, la quimioterapia
- Síndrome de serotonina con SSRI, MDMA, tramadol
- Fotosensibilidad (historia de envenenamiento animal)
- El supuesto “natural tan seguro” es el peligro, es un verdadero psicotrópico con una farmacología real.
✚Overdose signs
- Síntomas del síndrome de serotonina con combos
- Reacciones de fotosensibilidad
Comparación de categoría — Rendimiento y farmacia gris
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| St John's Wort (Hypericum) | OTC supplement — unregulated US; Rx-only Germany for depression | THE INTERACTION KING: induces CYP3A4 and P-gp — weakens oral contraceptives (pregnancies documented), HIV antiretrovirals, transplant immunosuppressants, blood thinners, chemotherapy; Serotonin syndrome with SSRIs, MDMA, tramadol | $8–$20 per bottle |
| AICAR (Acadesine) | Unscheduled | No human safety data — cancer-risk flags in cell studies; Sold as research chemical, zero quality control | ~$50–$150 per gram |
| Clenbuterol HCl | Not approved for human use | Racing heart, arrhythmia, tremors; Overdose: dangerous potassium shifts, cardiac events | ~$0.50–$2 per 40 mcg tablet |
| Anastrozole (Arimidex) | Rx-only | Bone density loss, joint pain with long-term use; Crash estrogen too low → depression, libido loss | ~$2–$8 per 1 mg tablet |
| Liraglutide (Saxenda) | Rx-only — not a controlled drug | Sold grey-market at huge markups with counterfeit/refilled pens; Nausea, pancreatitis risk | ~$200–$500 per pen grey-market |
| Naltrexone–Bupropion (Contrave) | Rx-only — not controlled | Bupropion lowers seizure threshold; Misuse for stimulant-like effect is possible but weak | ~$1–$4 per tablet grey-market |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does St John's Wort (Hypericum) look like?
Herba de flores amarillas; cápsulas, té, tinturas estandarizadas a hipericina/hiperforina
What are the signs of a St John's Wort (Hypericum) overdose?
Síntomas del síndrome de serotonina con combos; Reacciones de fotosensibilidad Call emergency services immediately.
How addictive is it?
REY DE LA INTERACCIÓN: induce CYP3A4 y P-gp – debilita los anticonceptivos orales (embarazos documentados), los antirretrovirales del VIH, los inmunosupresores de trasplante, los diluidores de la sangre, la quimioterapia Dependence can develop with regular use.