Performance & Grey-Market Pharma
5-HTP (5-Hydroxytryptophan)
Street names: 5-HTP, Oxitriptan, Griffonia extract, The serotonin precursor
Overdose? Act now. Call emergency services — say "unresponsive, not breathing". Give naloxone for opioid-like signs. Hotlines
⚡What it does
- Direct serotonin precursor: mild mood/sleep effects; post-MDMA recovery folklore
⚠Key risks
- SEROTONIN SYNDROME when stacked with SSRIs, MDMA, tramadol, or MAOIs — the 'harmless supplement' interacts fatally with the party calendar
- Heart-valve concern (chronic high-dose serotonin load, rodent signals)
- Eosinophilia-myalgia syndrome from a contaminated 1980s supply (historic, why quality matters)
- Daytime grogginess, vivid dreams
✚Overdose signs
- Agitation, clonus, fever (serotonin syndrome in combos)
- Nausea, drowsiness
Category comparison — Performance & Grey-Market Pharma
| Substance | Class | Top risks | Street price |
|---|---|---|---|
| 5-HTP (5-Hydroxytryptophan) | Supplement — unregulated US/UK/EU | SEROTONIN SYNDROME when stacked with SSRIs, MDMA, tramadol, or MAOIs — the 'harmless supplement' interacts fatally with the party calendar; Heart-valve concern (chronic high-dose serotonin load, rodent signals) | $10–$25 per bottle |
| AICAR (Acadesine) | Unscheduled | No human safety data — cancer-risk flags in cell studies; Sold as research chemical, zero quality control | ~$50–$150 per gram |
| Clenbuterol HCl | Not approved for human use | Racing heart, arrhythmia, tremors; Overdose: dangerous potassium shifts, cardiac events | ~$0.50–$2 per 40 mcg tablet |
| Anastrozole (Arimidex) | Rx-only | Bone density loss, joint pain with long-term use; Crash estrogen too low → depression, libido loss | ~$2–$8 per 1 mg tablet |
| Liraglutide (Saxenda) | Rx-only — not a controlled drug | Sold grey-market at huge markups with counterfeit/refilled pens; Nausea, pancreatitis risk | ~$200–$500 per pen grey-market |
| Naltrexone–Bupropion (Contrave) | Rx-only — not controlled | Bupropion lowers seizure threshold; Misuse for stimulant-like effect is possible but weak | ~$1–$4 per tablet grey-market |
Street prices are regional estimates. Potency and cuts vary constantly.
?Frequently asked questions
What does 5-HTP (5-Hydroxytryptophan) look like?
50–400 mg capsules from Griffonia simplicifolia seed extract
What are the signs of a 5-HTP (5-Hydroxytryptophan) overdose?
Agitation, clonus, fever (serotonin syndrome in combos); Nausea, drowsiness Call emergency services immediately.
How addictive is it?
SEROTONIN SYNDROME when stacked with SSRIs, MDMA, tramadol, or MAOIs — the 'harmless supplement' interacts fatally with the party calendar Dependence can develop with regular use.